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Content Tagged "Nikos Kyrpides"

JGI-Murdoch University rhizobial project

Rhizobia are soil bacteria that can form a symbiotic relationship with legumes such as common domesticated crops such as peas, beans or clovers. These symbiotic bacteria fix atmospheric nitrogen inside nodules formed on the legume roots contributing around 65% of the nitrogen currently used in agricultural production. A joint venture has been established between the… [Read More]

DOE JGI’s role in managing Human Microbiome Project data on redOrbit

At JGI, Kyrpides oversees projects such as GenePRIMP, a highly rated quality control program for genome sequencing, and GOLD, the Genomes On-Line Database. GenePRIMP stands for “Gene PRediction IMprovement Pipeline, and it consists of a series of computational units that can be used to significantly improve the overall quality of the predicted genes in any… [Read More]

DOE JGI’s role in managing Human Microbiome Project data on Medical News

“The HMP project catalog is a unique worldwide resource,” says molecular biologist Nikos Kyrpides of Berkeley Lab’s Genomics Division, who heads the Genome Biology and Metagenomics Programs for the Joint Genome Institute (JGI) and is the co-principal investigator of the DACC. “It has a central role in the HMP, not only in maintaining the list… [Read More]

DOE JGI’s role in managing Human Microbiome Project data

At JGI, Kyrpides oversees projects such as GenePRIMP, a highly rated quality control program for genome sequencing, and GOLD, the Genomes On-Line Database. GenePRIMP stands for “Gene PRediction IMprovement Pipeline, and it consists of a series of computational units that can be used to significantly improve the overall quality of the predicted genes in any… [Read More]

GenePRIMP QC tool on Genetic Engineering & Biotechnology News

The program, said Pati, identifies gene-calling errors such as potentially incorrect gene start and end positions, large overlaps between genes, fragmented genes and missed genes. Gene-calling errors, noted Pati, can range from two percent to as much as 30 percent of the original genes identified in the genome and are dependent on many factors, such… [Read More]

GenePRIMP QC tool on PhysOrg

“There are a lot of different tools used for predicting genes in prokaryotes,” Kyrpides said. “The major problem we have is that they all produce very variable results. This impedes our ability to compare genomes sequenced and annotated from various sources, as they use different tools for gene prediction. GenePRIMP is not substituting any of… [Read More]

GenePRIMP QC tool on redOrbit

“With GenePRIMP we have achieved a major breakthrough in the improvement of the quality of structural annotations such as gene predictions,” said Genome Biology Program head and study senior author Nikos Kyrpides. He pointed out that using GenePRIMP offers researchers three major advantages: high quality results with reduced errors; an approach that can be used… [Read More]

GenePRIMP QC tool on ScienceDaily

Pati said GenePRIMP significantly reduces the amount of time scientists spend checking the whole genome by specifically highlighting errors that need to be manually corrected.  Read more on ScienceDaily. [Read More]

GenePRIMP QC tool on Medical News Today

More than a thousand microbial genomes have been sequenced at various sequencing centers in the past 15 years to better understand their roles in tasks ranging from bioenergy to health to environmental cleanup.  Read more on Medical News Today. [Read More]

GenePRIMP QC tool on EurekAlert

To assist in checking the quality of the microbial genomic DNA sequences generated before they are submitted to the federally funded public archive GenBank, the U.S. Department of Energy (DOE) Joint Genome Institute (JGI) has introduced a quality control tool known as the Gene Prediction IMprovement Pipeline or GenePRIMP. GenePRIMP is described in a paper… [Read More]