News & Publications

A graphic flowchart showing how CRAGE and CRISPR work together

August 22, 2022

Extracting the Secrets of Secondary Metabolites

Microbial secondary metabolites, those molecules not essential for growth yet essential for survival, may now be easier to characterize following a JGI proof-of-concept study in which researchers paired CRAGE and CRISPR technologies. [Read More]

Chlamydomonas is an insightful little alga that holds clues to leveraging other organisms for sustainable biofuel production. [Image: MPI-CBG, Dresden]

August 11, 2022

JGI at 25: The Little Alga That Could

Since the JGI’s sequencing of Chlamydomonas reinhardtii — the tiny alga with a mighty impact — became available, those sequences have been cited in almost one-fourth (23.8%) of publications focused on that specific algae. The reference genome is cited in roughly 10% of all since-released publications on green algae. [Read More]

Data yielded from RIViT-seq increased the number of sigma factor-gene pairs confirmed in Streptomyces coelicolor from 209 to 399. Here, grey arrows denote previously known regulation and red arrows are regulation identified by RIViT-seq; orange nodes mark sigma factors while gray nodes mark other genes. (Otani, H., Mouncey, N.J. Nat Commun 13, 3502 (2022). https://doi.org/10.1038/s41467-022-31191-w)

July 15, 2022

Streamlining Regulon Identification in Bacteria

Using RIViT-seq technology, researchers were able to identify the target genes of transcription factors in Streptomyces coelicolor. [Read More]

The common bean (Phaseolus vulgaris) includes pinto beans, kidney beans, black beans, navy beans and more. (Image Credit: TK)

July 11, 2022

JGI at 25: Building a Better Bean

The JGI’s original reference genome for Phaseolus vulgaris has been instrumental in creating a hardier, higher-yield bean. [Read More]