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… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics … Exploring the fascinating world of giant viruses, which challenge our understanding of viral … giant viruses, which possess genomes and particle sizes that rival those of cellular organisms. Giant viruses …

… genomic information from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct … Profile HMM search across all IMG metagenomes, capturing sequence diversity for proteins …

… however they do so under strong constraints exerted by viruses. Research in the viral genomics group aims at … in virus:host interaction and host cell take-over by viruses, and attempts to evaluate ecosystem-level impacts of … from metagenomes, our understanding of the impacts of these viruses on microbiome processes is still limited. One key …

… archaea, and micro-eukaryoes, along with their associated viruses and mobile genetic elements. Beyond exploring and … computational tools for analyzing viral fragments via IMG/VR and methods to capture  environmental viral populations. … The IMG/M system serves as a community resource for comparative …

… or NPAtlas, a freely accessible natural products structure database, which is going to be just invaluable to the … that we’ve put together to try and create an open source database of all known microbial natural products. So if you … cluster. So either both of those pools have to increase in size dramatically, or there has to be a significant …

… types of particulate like 2.5, 10 PPMs and just the size of the particle and how far they can actually travel. … to help our users. So for those who are familiar with JGI’s IMG data portal , the Integrated Microbial Genomics, there … and InterProScan. And all of those have ended up in the SMC database. There’s a web front end for it, and it’s just a …

… from which potentially natural product could be biosynthesized, then you need to develop enabling technologies. ie … so everybody, readers of the library, can come to our databases and look for the specific information they are … fundamental medicine. And this is mass data, the huge databases, is probably also going to inspire us to really …

… with microeukaryotes. The program also studies giant viruses. Key research areas include terrestrial … The IMG/M system serves as a community resource for comparative … the context of reference isolate genomes included from the IMG/M system. … IMG/PR is a plasmid genome resource featuring the largest …

… (median/75th percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less … Environmental transcript sequence Assembly, annotation ( IMG/M ), mapping 273/273 Metagenome Cell Enrichments … amplification prior to sequencing. Assembly, annotation ( IMG/M ) Depends on project Metagenome Minimal Draft …

… of searching the internet, searching literature, and making databases. Because that’s what I noticed is really a … even in primary metabolism or in certain snips of viruses or something. I don’t know. Then I think making sure … in the past, we’ve had these monolithic databases, NCBI and IMG , that have a lot of data and really useful data, really …

… symbionts, detrimental microbial pathogens, and associated viruses that all contribute to a dynamic ecosystem. We are … and complex ecosystem that includes bacteria, fungi, viruses. Resident viruses can be found in a myriad of bacterial strains, …

… him about more recent work like ActDES, which is a curated database of actinobacteria for evolutionary studies, and … are microbes that will actually redefine how you synthesize nucleotides. Stuff that are at the core of what we call … that in certain niches, ecological niches, probably Marc Chevrette ‘s contribution to talk about this, he’s very …