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… and machine learning to identify new divergent lineages and expand the Tree of Life. We then investigate … Cataloging Earth's microbial lineages through advanced genomic techniques and … to adapt to live in Earth's most extreme environments, from deep-sea oceanic fluids to hypersaline lakes and …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, … provides high-quality, large-scale genomic data to advance microbial research that drives sustainable solutions in … The Microbial Program focuses on using advanced sequencing … genome sequencing of underexplored bacterial and archaeal lineages that are important for bioeconomy applications. By …

… program for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will … by the Joint Genome Institute, builds upon thousands of microbial genomes that have been sequenced by the JGI though … talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in ongoing …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic properties encoded … focuses on the assembly of metagenomic sequence data into microbial genomes, which is of fundamental value to …

… genetic elements. Beyond exploring and characterizing microbial diversity, work in the Metagenome Program uses several experimental approaches to assess microbial activity across ecosystems.  By studying microbial communities and their interactions, the Program …

… Molecular Cell 2019) and massive reconstruction of genomes from uncultivated microbes (Nature 2019). Other projects in … A global metagenomic map of urban microbiomes and antimicrobial resistance. Cell . 184(13):3376-3393 Almeida A, et … Acids Res.  45(D1):D457-D465. Paez-Espino, D. et al. (2016) Uncovering Earth’s virome.  Nature   536:425-30 Kyrpides NC. …

… interactions with their environments and with each other, from defending against predators to aiding in symbiotic … (BGCs) being expressed. The program works to uncover these hidden biochemical resources by exploring the genetic … broader goal of enhancing biotechnological applications, from biofuel production to improving the resilience and …

… such effort is targeted at environmental cells that are from candidate phyla, major branches in the phylogenetic … in 1985, which highlights our skewed understanding of microbial metabolism towards a minority of cultivated … as phylogenetic anchors for metagenomes studies.  While uncovering the metabolic potential of uncultivated lineages …

… including fungal and bacterial symbionts, detrimental microbial pathogens, and associated viruses that all … how plants self-organize, influence, and are influenced by microbial partners. We use a variety of genomics-powered …

… parameters driving virus:host dynamics in environmental microbial communities. This involves both experimental and … of phage and virus genomes have been assembled and reported from metagenomes, our understanding of the impacts of these … invaluable information on virus diversity and activity in microbial communities, however they can only provide a …

… exploration of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With … mass spectrometry-based methods to analyze metabolites from a wide range of biological and environmental samples — … systems can provide novel insights into the impact of microbial symbionts and their hosts on ecosystems.   …

… in the project by watching Amanda Hurley’s presentation from the 2019 JGI Genomics of Energy & Environment Meeting.] … here is metabolomics. So this is a way to get a snapshot of all of the chemistry that a microbe produces. And … Canada. I just got back from a conference in Canada on antimicrobial resistance sponsored by the Garner foundation. And …