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… Survey of Setaria's natural diversity reveals seed dispersal in wild populations for the first time. For years, … years, farmers have selected for cereal plants without this shattering trait – referring to the moment when the cluster … genomics in support of DOE missions related to clean energy generation and environmental characterization and cleanup. …

… to regulate Earth's carbon balance, to exploring the genetic basis of how plants have naturally adapted to varied … climate and soil conditions around the globe to identify genes to improve our domesticated species.  The program supports the development of next-generation biofuels by studying perennial grasses and …

… genomics with metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy … techniques and computational tools, the program supports foundational research related to soil nutrient cycling and … JGI scientists are able to link metabolic activity with gene expression, providing deeper insights into functional …

… bit more into fungi and learning the differences of all the genetic differences and then expanded on on that knowledge … seems to be a new structure, and the microorganisms are novel. I mean, we have Streptomyces , but they’re new … I think, are a good way to get people engaged and sort of seed some ideas for people in the community, I think. Also, …

… and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells us about forthcoming … time called Genbiotics , which was a large program to find novel antibiotics. And this particular project focused … who share an idea, and then you extend with kind of a seed community. Maybe 10 or 20 people who are enthusiastic …

… It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … supposed to be orthogonal. And then we much to our chagrin found that they had the same conserved polyketide synthase … in order to put them together to build pathways, to make novel compounds, or to find analogs. And that was Warp …

… ALISON TAKEMURA: I know that it’s looking in the genome for genetic elements of interest, you know, something like … sequencing if you were rich enough. [CHUCKLES] And once you found a little piece of something that looked like it was a … machine learning really would help distinguish and predict novel gene clusters. DAN UDWARY: Yeah, it certainly could. …

… an exploration into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a … we now know that organic molecules in the ocean are the foundation of communication by chemical means, of survival … the most effective application, of marine molecules in general. DAN UDWARY: Maybe can you explain to our audience …

… After I got my undergraduate degree, which was in general biology, I joined the Peace Corps. And when I was … ITS which we thought would identify to species”… he’s now found that some fungi have different ITS sequences in their … of insects are sensitive to mycotoxins and if you have a seed – I mean, this is bandied about – let’s say that has a …

… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and … of Life. We then investigate the coding potential to find novel functions that may impact microbiome structure and … and complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. …

… oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that oftentimes turn off these biosynthetic gene clusters. And so we've been really interested in trying … as what we initiated our search around. And so we found examples of those, and then looked for NRPSs nearby, …

… including User Facilities like the JGI, through its Genesis Mission. Launched in 2025, the initiative aims to … and AI agents to solve key national challenges. The Genesis Mission consortium will connect leading industry and … among members that catalyze data flows and promote novel data applications. As a large-scale data generator, …