Search

… recognized and credited for their work, while also adhering to the authorship policies of the journal in which the … that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … acknowledgment (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, …

… Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables exploration of energy … terrestrial biogeochemical processes, development of high performance plants and microbes, and understanding …

… for another episode of Natural Prodcast. Right now I’m working on this the afternoon of the day I’m due to release it, … and he has a project with the JGI to synthesize the genes for and explore the chemistry of quorum sensing … we’ll say methyl so we call them methylotrophs [ muh-thigh-luh-trophs ]. This is like, every square is a …

… and BiG-SLiCE, and now the BiG-FAM database of biosynthetic gene cluster families. And he tells us about forthcoming … least a certain level of similarity. So if similarity was higher than a certain kind of volume. And if you do that, … now let’s look into detail, let’s make phylogenies of the underlying genes, let’s make alignments of those gene …

… of these compounds, which, in turn, translate into a high chemical diversity. So that’s just the type of … the active site of an enzyme. So there is no promiscuity, generally speaking, in primary metabolism. Nevertheless, … that are produced, and we don’t know what potentially other targets, if there are actually other targets. So Firn and …

… back to a new session of Natural Prodcast. I’ve got two things I wanted to tell you about in this introduction. First … It was unpublished at that point. But people would push out gene clusters maybe once a month at most. Maybe twice a … So I built a lab to do that. And then yes, we had several targets– mechanistic enzymology targets and biosynthetic …

… of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, … America brought to the UK? ROGER:  Yeah, it’s difficult to generalize, of course, but I felt overall that the British … and so the quality – the data quality – was reasonably high. And yeah, it gave it gave us enough enough pairs of …

…   Our Sequencing Technologies Group is well-integrated across JGI …   Overview of sequencing products The JGI operates highly scaled short- and long-read sequencing pipelines. … (quality assurance/quality control [QA/QC]), large-scale liquid handling automation, and sequence analysis. …

… bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to identify new divergent lineages and expand … complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. …

… mining and the directions it might take in the future. I highly recommend it. I’ll link to it in the show notes. … of it. So it wasn’t only chemistry or only biochemistry or genetics. It was also ecology. It was also evolution. It was … Usually, in a lot of cases, we still have to go through publications to get proteins, and their functions, and all …