DOE Joint Genome Institute

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    A vertical tree stump outdoors with about a dozen shiitake mushrooms sprouting from its surface.
    Tracing the Evolution of Shiitake Mushrooms
    Understanding Lentinula genomes and their evolution could provide strategies for converting plant waste into sugars for biofuel production. Additionally, these fungi play a role in the global carbon cycle.

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    Soil Virus Offers Insight into Maintaining Microorganisms
    Through a collaborative effort, researchers have identified a protein in soil viruses that may promote soil health.

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    Data yielded from RIViT-seq increased the number of sigma factor-gene pairs confirmed in Streptomyces coelicolor from 209 to 399. Here, grey arrows denote previously known regulation and red arrows are regulation identified by RIViT-seq; orange nodes mark sigma factors while gray nodes mark other genes. (Otani, H., Mouncey, N.J. Nat Commun 13, 3502 (2022). https://doi.org/10.1038/s41467-022-31191-w)
    Streamlining Regulon Identification in Bacteria
    Regulons are a group of genes that can be turned on or off by the same regulatory protein. RIViT-seq technology could speed up associating transcription factors with their target genes.

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    The switchgrass diversity panel growing at the Kellogg Biological Station in Michigan. (David Lowry)
    Mapping Switchgrass Traits with Common Gardens
    The combination of field data and genetic information has allowed researchers to associate climate adaptations with switchgrass biology.

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    Artist rendering of genome standards being applied to deciphering the extensive diversity of viruses. (Illustration by Leah Pantea)
    Expanding Metagenomics to Capture Viral Diversity
    Along with highlighting the viruses in a given sample, metagenomics shed light on another key aspect of viruses in the environment — their sheer genetic diversity.

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    Photograph of a stream of diatoms beneath Arctic sea ice.
    Polar Phytoplankton Need Zinc to Cope with the Cold
    As part of a long-term collaboration with the JGI Algal Program, researchers studying function and activity of phytoplankton genes in polar waters have found that these algae rely on dissolved zinc to photosynthesize.

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    Silver Age of GOLD Introduces New Features
    The Genomes OnLine Database makes curated microbiome metadata that follows community standards freely available and enables large-scale comparative genomics analysis initiatives.

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    Graphical overview of the RNA Virus MetaTranscriptomes Project. (Courtesy of Simon Roux)
    A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
    Researchers combed through more than 5,000 data sets of RNA sequences generated from diverse environmental samples around the world, resulting in a five-fold increase of RNA virus diversity.

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    HPCwire Editor's Choice Award (logo crop) for Best Use of HPC in the Life Sciences
    JGI Part of Berkeley Lab Team Awarded Best Use of HPC in Life Sciences
    The HPCwire Editors Choice Award for Best Use of HPC in Life Sciences went to the Berkeley Lab team comprised of JGI and ExaBiome Project team, supported by the DOE Exascale Computing Project for MetaHipMer, an end-to-end genome assembler that supports “an unprecedented assembly of environmental microbiomes.”

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    Digital ID card with six headshots reads: Congratulations to our 2022 Function Genomics recipients!
    Final Round of 2022 CSP Functional Genomics Awardees
    Meet the final six researchers whose proposals were selected for the 2022 Community Science Program Functional Genomics call.

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    CSP New Investigators FY23 R1
    JGI Announces First Round of 2023 New Investigator Awardees
    Twice each year we look for novel research projects aligned with DOE missions and from PIs who have not led any previously-accepted proposals through the CSP New Investigator call.

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    screencap from Amundson and Wilkins subsurface microbiome video
    Digging into Microbial Ecosystems Deep Underground
    JGI users and microbiome researchers at Colorado State University have many questions about the microbial communities deep underground, including the role viral infection may play in other natural ecosystems.

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    2022 JGI-UC Merced interns (Thor Swift/Berkeley Lab)
    Exploring Possibilities: 2022 JGI-UC Merced Interns
    The 2022 UC Merced intern cohort share how their summer internship experiences have influenced their careers in science.

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    Using Team Science to Build Communities Around Data
    As the data portals grow and evolve, the research communities further expand around them. But with two projects, communities are forming to generate high quality genomes to benefit researchers.

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    Cow Rumen and the Early Days of Metagenomics
    Tracing a cow rumen dataset from the lab to material for a hands-on undergraduate research course at CSU-San Marcos that has since expanded into three other universities.

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All JGI Features
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August 24, 2004

JGI Announces Community Sequencing Program Portfolio

WALNUT CREEK, CA–Despite the perception that the genetic diversity among animals–ranging from humans to worms–is enormous, the reality is that it pales in comparison to the diversity between the microbes that make up the bulk of the biomass on the planet. Accordingly, to close conspicuous gaps in our understanding of the tree of life, the…

June 10, 2004

JGI, VBI Help Unravel Sudden Oak Death & Soybean Disease

WALNUT CREEK, CA–Researchers are closer now to thwarting two related plant pathogens, one causing “Sudden Oak Death” (SOD) and another responsible for a devastating soybean disease, thanks to the DNA sequence produced by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), in collaboration with the Virginia Bioinformatics Institute (VBI). The projects received nearly…

May 2, 2004

JGI Decodes Wood and Toxic Waste-Degrading Fungus Genome

Walnut Creek, CA–The United States Department of Energy (DOE) Joint Genome Institute (JGI) announces today the publication of a high-quality draft genome sequence of the white rot fungus, Phanerochaete chrysosporium. These are the only known microbes capable of efficiently degrading the recalcitrant aromatic plant polymer lignin, one of the most abundant natural materials on earth….

March 31, 2004

Gene-Rich Human Chromosome 19 Sequence Completed

Walnut Creek, CA–The United States Department of Energy (DOE) Joint Genome Institute (JGI) and Stanford University report today the completion of the sequencing of human chromosome 19, the most gene-rich of all the human chromosomes. This achievement is described in the April 1, 2004 edition of the journal Nature. “Culminating 18 years of research, this…

February 2, 2004

First Genomes Revealed from Environmental Microbial Communities

Walnut Creek, CA–Researchers from the Department of Energy Joint Genome Institute (JGI) and the University of California, Berkeley, report the first genomic characterization of a microbial community. The results announced online February 1st in the journal Nature reveal how the genetic identities of microorganisms thriving in toxic conditions, “extremophiles,” were recovered from a natural biofilm…

January 20, 2004

JGI Launches Community Sequencing Program

The Department of Energy’s Joint Genome Institute (JGI) is poised for a resounding response to the age-old question, “If we build it, will they come?” Already, collaborators are queuing up to take advantage of one of the world’s most powerful DNA sequencing facilities for the debut of DOE’s Community Sequencing Program (CSP). “The primary goal…

August 13, 2003

Genomes of Tiny Microbes Yield Clues to Global Climate Change

By analyzing the genomes of several microscopic ocean-dwelling organisms sequenced at the U.S. Department of Energy’s Joint Genome Institute (JGI), scientists are gaining new insights into how the planet’s oceans affect its climate. Comparative studies of four types of cyanobacteria–“photosynthetic” microbes that derive energy from sunlight, just like plants–were published today on the websites of…

May 5, 2003

DOE Joint Genome Institute and Diversa Corp. Announce Large-Scale Microbial Sequencing Collaboration

The U.S. Department of Energy’s Joint Genome Institute (JGI) and Diversa Corporation (Nasdaq: DVSA) today announced a collaboration to discover and sequence novel microbial genomes found in a diverse range of unique habitats. Under the collaboration, Diversa will use its proprietary technologies to extract DNA from environmental samples and make gene libraries, while JGI will…

January 28, 2003

Eddy Rubin Named JGI Director

Dr. Edward M. (Eddy) Rubin, an internationally known geneticist and medical researcher, has been named Director of the U.S. Department of Energy’s Joint Genome Institute (JGI). Rubin was also named Director of the Genomics Division at Lawrence Berkeley National Laboratory (LBNL). Rubin, who had been serving as Interim Director of JGI since spring 2002, was…

December 12, 2002

Sea Squirt DNA Sheds Light on Vertebrate Evolution

WALNUT CREEK, CA — The streamlined genome of Ciona intestinalis, a common sea squirt closely related to vertebrates on the evolutionary tree, is providing new clues about the origins of key vertebrate systems and structures including the human hormone, nervous and immune systems. In an article for the December 13, 2002 edition of the journal…

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