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… and viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine … Studying microorganisms that thrive in Earth's most extreme environments: We study genomic innovation that allowed microbes to adapt to …

… now?  MARCY: Sure. So my lab has really converged on the study of host-microbe chemistry. And the interactions– As … that the squid is one– is we work on a lot of host-microbe symbiosis at this point. But the squid is probably the most … you try to tackle that? Would you do that through metabolomics or sequence or both or–?  MARCY: So we do so much more …

… influenced by microbial partners. We use a variety of genomics-powered tools to study this complexity, including single-cell and spatial transcriptomics barcode-based genetics (RB-TnSeq), and computational … experimental and computational approach, we employ various omics technologies, strain engineering and experimental …

… The JGI’s Metabolomics Program works to uncover the roles of small molecules … and ecosystems at the molecular level. Integrating genomics with metabolomics fuels the discovery  of novel metabolites, genes, and … The Metabolomics Program is focused on understanding the critical roles …

… constraints exerted by viruses. Research in the viral genomics group aims at improving our collective understanding … ecosystem-level impacts of viral infections. The Viral Genomics Group is hosted within the Environmental Genomics group . Research Team … ( Who is active when/where, and how? ). The JGI Viral Genomics group attempts to address this question in natural …

… on the application of  function-driven single-cell genomics . Here, single cells are characterized and selected as … Chris Rinke: Research Officer, Australian Centre for Ecogenomics Patrick Schwientek: Cofounder & CTO, Oralta … virus diversity and host interactions through global metagenomics.” Nature 578(7795): 432-436 (2020). Seshadri R., Leahy …

… a revolution brought on by rapid developments in genomics and other omics technologies.  The exponential growth of DNA … Unraveling the functional dark matter through global metagenomics. Nature . 622(7983):594-602. Camargo AP. et al. (2023) … virus diversity and host interactions through global metagenomics. Nature 578(7795):432-436 Sberro H, et al. (2019) …

… The CSP Functional Genomics call is to enable users to perform state-of-the-art functional genomics research and to help them translate genomic … emphasis is on projects leveraging JGI’s DNA synthesis and ‘omics capabilities to enhance understanding of gene and …

…   Metabolomics strengthens -omics technologies at the JGI by identifying the actual … system behavior.  Through this identification, metabolomics enables functional genome annotation, improves … the discovery of new molecules and pathways. The JGI Metabolomics Platform delivers rich metabolite profiles from …

… kept looking for open jobs that said, we want a chemist to study the ocean. And I didn’t find a single job … to do something completely new. And that is to begin to study the organic chemistry of life in the sea. And he … all over the world and bringing samples into the lab for study. DAN UDWARY: Where were you on the timing of that …

… And he tells us about forthcoming efforts in paired-omics data sets and seeking to interpret function from BGCs. … what was this bacterium, and why did your group want to study it? Marnix Medema: You mean the PhD project that I … of hooks into IMG’s data. IMG being Integrated Microbial Genomics at JGI, a large data set of bacterial genomes. And so …