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… learning to identify new divergent lineages and expand the Tree of Life. We then investigate the coding potential to find novel … discovering and characterizing giant viruses, which possess genomes and particle sizes that rival those of cellular … the traditional boundaries between viruses and cellular life, providing unique insights into viral evolution and …

… The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, environmental … and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the … The Fungal & Algal Program harnesses cutting-edge sequencing technologies …

… from candidate phyla, major branches in the phylogenetic tree without cultivated representatives. The “Great … Phylogenetic diversity estimates show that the gap between cultivated and uncultivated Bacteria and Archaea … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … working with him.  We talk about his father, the legendary marine natural products chemist, Richard Moore, and get into seaweed, robots, algae, and biocatalysis — and he makes fun of me a lot, …

… of Oceanography in San Diego. Bill is a pioneer of marine natural products, getting into the ocean and looking … new. And that is to begin to study the organic chemistry of life in the sea. And he looked at me and he said, you know, … So, this was when we started saying, we have to have the genomes. We have to look at the full picture of these. And …

… 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science … 2018, Molecular Cell 2019) and massive reconstruction of genomes from uncultivated microbes (Nature 2019). Other … (2021) CheckV assesses the quality and completeness of metagenome-assembled viral genomes. Nature Biotechnol . …

… UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural … come from all kinds of disparate environments. There’s some marine. There’s some soil samples. There’s human gut … of if there’s anything kind of in my normal day-to-day life where there are 87,000 kinds. What fraction of those …

… in the early 2000s called Ecopia, which was a very early genome mining company, back when DNA sequencing of natural … has to have a story. And it can be looking for drugs from marine organisms, in which case you get to go to exotic … So to me, to us, about 6 years ago, we thought the big gap in genome mining is not knowing if something is active …

… food, medicine, and bioenergy crops. But most available genomes are from narrow swaths of the plant tree of life. One project aims to change that. …

… UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a podcast about natural … at some topic that I’m working with about now. I made a tree of different compounds, and I’d looked at it from an … quality. Yeah, for sure. NADINE ZIEMERT: Yeah, Dan… it’s a marine actinomycete bacterium. So they look kind of like …

… NOTICE The Data Portal application has replaced the JGI Genome Portal . Book a session via the appointment calendar … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic data, open to … for comprehensive access to information regarding genome and metagenome sequencing projects, and their …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … But where taxol comes from is, from the bark of the yew tree, is where it was originally discovered. And so that … might be as critical or it might be as big a part of its life as metabolizing sugars, but it’s something that we …