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    Data yielded from RIViT-seq increased the number of sigma factor-gene pairs confirmed in Streptomyces coelicolor from 209 to 399. Here, grey arrows denote previously known regulation and red arrows are regulation identified by RIViT-seq; orange nodes mark sigma factors while gray nodes mark other genes. (Otani, H., Mouncey, N.J. Nat Commun 13, 3502 (2022). https://doi.org/10.1038/s41467-022-31191-w)
    Streamlining Regulon Identification in Bacteria
    Regulons are a group of genes that can be turned on or off by the same regulatory protein. RIViT-seq technology could speed up associating transcription factors with their target genes.

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    (PXFuel)
    Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
    In a special issue of the journal Synthetic Biology, JGI scientific users share how they’ve worked with the JGI DNA Synthesis Science Program and what they’ve discovered through their collaborations.

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    A genetic element that generates targeted mutations, called diversity-generating retroelements (DGRs), are found in viruses, as well as bacteria and archaea. Most DGRs found in viruses appear to be in their tail fibers. These tail fibers – signified in the cartoon by the blue virus’ downward pointing ‘arms’— allow the virus to attach to one cell type (red), but not the other (purple). DGRs mutate these ‘arms,’ giving the virus opportunities to switch to different prey, like the purple cell. (Courtesy of Blair Paul)
    A Natural Mechanism Can Turbocharge Viral Evolution
    A team has discovered that diversity generating retroelements (DGRs) are not only widespread, but also surprisingly active. In viruses, DGRs appear to generate diversity quickly, allowing these viruses to target new microbial prey.

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    Photograph of a stream of diatoms beneath Arctic sea ice.
    Polar Phytoplankton Need Zinc to Cope with the Cold
    As part of a long-term collaboration with the JGI Algal Program, researchers studying function and activity of phytoplankton genes in polar waters have found that these algae rely on dissolved zinc to photosynthesize.

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    This data image shows the monthly average sea surface temperature for May 2015. Between 2013 and 2016, a large mass of unusually warm ocean water--nicknamed the blob--dominated the North Pacific, indicated here by red, pink, and yellow colors signifying temperatures as much as three degrees Celsius (five degrees Fahrenheit) higher than average. Data are from the NASA Multi-scale Ultra-high Resolution Sea Surface Temperature (MUR SST) Analysis product. (Courtesy NASA Physical Oceanography Distributed Active Archive Center)
    When “The Blob” Made It Hotter Under the Water
    Researchers tracked the impact of a large-scale heatwave event in the ocean known as “The Blob” as part of an approved proposal through the Community Science Program.

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    A plantation of poplar trees. (David Gilbert)
    Genome Insider podcast: THE Bioenergy Tree
    The US Department of Energy’s favorite tree is poplar. In this episode, hear from ORNL scientists who have uncovered remarkable genetic secrets that bring us closer to making poplar an economical and sustainable source of energy and materials.

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    HPCwire Editor's Choice Award (logo crop) for Best Use of HPC in the Life Sciences
    JGI Part of Berkeley Lab Team Awarded Best Use of HPC in Life Sciences
    The HPCwire Editors Choice Award for Best Use of HPC in Life Sciences went to the Berkeley Lab team comprised of JGI and ExaBiome Project team, supported by the DOE Exascale Computing Project for MetaHipMer, an end-to-end genome assembler that supports “an unprecedented assembly of environmental microbiomes.”

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    With a common set of "baseline metadata," JGI users can more easily access public data sets. (Steve Wilson)
    A User-Centered Approach to Accessing JGI Data
    Reflecting a structural shift in data access, the JGI Data Portal offers a way for users to more easily access public data sets through a common set of metadata.

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    Phytozome portal collage
    A More Intuitive Phytozome Interface
    Phytozome v13 now hosts upwards of 250 plant genomes and provides users with the genome browsers, gene pages, search, BLAST and BioMart data warehouse interfaces they have come to rely on, with a more intuitive interface.

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    screencap from Amundson and Wilkins subsurface microbiome video
    Digging into Microbial Ecosystems Deep Underground
    JGI users and microbiome researchers at Colorado State University have many questions about the microbial communities deep underground, including the role viral infection may play in other natural ecosystems.

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    Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical output due to growth and viability constraints. Cell extracts provide an alternative format for chemical synthesis in the absence of cell growth by isolating the soluble components of lysed cells. By separating the production of enzymes (during growth) and the biochemical production process (in cell-free reactions), this framework enables biosynthesis of diverse chemical products at volumetric productivities greater than the source strains. (Blake Rasor)
    Boosting Small Molecule Production in Super “Soup”
    Researchers supported through the Emerging Technologies Opportunity Program describe a two-pronged approach that starts with engineered yeast cells but then moves out of the cell structure into a cell-free system.

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    These bright green spots are fluorescently labelled bacteria from soil collected from the surface of plant roots. For reference, the scale bar at bottom right is 10 micrometers long. (Rhona Stuart)
    A Powerful Technique to Study Microbes, Now Easier
    In JGI's Genome Insider podcast: LLNL biologist Jennifer Pett-Ridge collaborated with JGI scientists through the Emerging Technologies Opportunity Program to semi-automate experiments that measure microbial activity in soil.

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    A view of the mangroves from which the giant bacteria were sampled in Guadeloupe. (Hugo Bret)
    Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
    Harnessing JGI and Berkeley Lab resources, researchers characterized a giant - 5,000 times bigger than most bacteria - filamentous bacterium discovered in the Caribbean mangroves.

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    In their approved proposal, Frederick Colwell of Oregon State University and colleagues are interested in the microbial communities that live on Alaska’s glacially dominated Copper River Delta. They’re looking at how the microbes in these high latitude wetlands, such as the Copper River Delta wetland pond shown here, cycle carbon. (Courtesy of Rick Colwell)
    Monitoring Inter-Organism Interactions Within Ecosystems
    Many of the proposals approved through JGI's annual Community Science Program call focus on harnessing genomics to developing sustainable resources for biofuels and bioproducts.

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    Coloring the water, the algae Phaeocystis blooms off the side of the sampling vessel, Polarstern, in the temperate region of the North Atlantic. (Katrin Schmidt)
    Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
    As warm-adapted microbes edge polewards, they’d oust resident tiny algae. It's a trend that threatens to destabilize the delicate marine food web and change the oceans as we know them.

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Our Projects
Home › CSP Plans
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August 1, 2015

Developing Colletotrichium genomics resources

The genus Colletotrichum contains at least 150 species divided into nine major clades, and one of the largest is the Colletotrichum acutatum species complex (CAs). Species belonging to this complex are associated with diseases that infect a wide diversity of crop plants worldwide, and some insects as well. Despite being one of the largest lineages… [Read More]

August 1, 2015

Gene expression profiling in bioenergy grasses

Sugarcane and Miscanthus are closely related to the DOE JGI Flagship plant Sorghum and comprise the Andropogoneae, a tribe of highly productive grasses prominent in energy production. Miscanthus is a nascent DOE JGI flagship, pending completion of a reference genome draft. Sugarcanes and Miscanthus are both polyploids with complex genomes, which has limited the use of modern,… [Read More]

August 1, 2015

Acquired immunity in poplar

Populus trichocarpa was the first tree species whose whole genome was sequenced, assembled and annotated by the DOE JGI for bioenergy applications. This project has two major aims: 1) document the evolutionary process (i.e., the accumulation of mutations) that a single poplar tree undergoes during its lifetime; and, 2) examine the hypothesis that perennial plants… [Read More]

August 1, 2015

Columbia River estuary systems biology

River and ocean end members are heavily populated areas subjected to powerful physical forces and vulnerable to the impacts of human activity and climate change. Estuaries buffer the ocean from the effects of land loads of reactive nitrogen, but can also enhance microbial production of the greenhouse gases carbon dioxide, methane and nitrogen dioxide. This… [Read More]

August 1, 2015

Dung fungi as a model system

Fungi are the primary decomposers of organic matter in terrestrial ecosystems. In order to understand decomposition, it is critical to know how species interact and why species identities change during the decomposition process. This project aims to improve understanding of the community basis for fungal decomposition by developing a model system for decomposition using coprophilous… [Read More]

August 1, 2015

Insights into Coral-Symbiodinium symbiosis

Coral reefs are threatened tropical marine ecosystems whose fundamental unit is the reef building coral. A coral colony is a complex community comprised of both the coral host and its associated microbiome, the coral holobiont. The coral microbiome is important in shaping host health but its metabolic contribution to the coral holobiont is poorly understood,… [Read More]

August 1, 2015

Genomic diversity of Pseudomonas

Pseudomonas is a large and heterogeneous genus, and these bacteria exhibit varied lifestyles in a wide range of environments, including soil, water, plant surfaces, and animals. Due to their roles in bioremediation, biological control, diseases of plants and animals, and many other environmental processes, the metabolic capacities and ecological functions of these bacteria have been… [Read More]

August 1, 2015

Driving the carbon cycle in the dark ocean

The oceans contain the largest reservoir of rapidly exchangeable carbon yet also effectively sequester carbon from the atmosphere for thousands of years. The drivers of this delicate equilibrium are the abundant marine microbial communities ubiquitously present in the Earth’s oceans. This project will provide insight into the major metabolic pathways and key carbon compounds involved… [Read More]

August 1, 2015

Insights on uncultured microbes in wastewater

Currently, anaerobic wastewater treatment serves as an essential municipal waste remediation strategy due to its low cost and efficient waste removal, and the production of methane as a sustainable energy source. To effectively enhance process operation for bioenergy recovery, however, researchers need to better understand the microbial ecology of wastewater treatment. Three primary ecological groups–fermenters,… [Read More]

August 1, 2015

Exploiting Actinobacteria genomes

Actinobacteria are ubiquitously distributed in both aquatic and terrestrial ecosystems and have developed diverse lifestyles, as well free living as in association with a wide variety of eukaryotes. Next to Proteobacteria and Firmicutes, Actinobacteria constitute the third most populated phylum among the Bacteria. This project calls for sequencing the genomes of 1,000 environmental isolates (type… [Read More]
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