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A Community Resource for Secondary Metabolite Researchers
… user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most … growth and reproduction—most organisms produce a set of "secondary metabolites," chemical compounds that often … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence …
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A Model System for Perennial Grasses
… Panicum hallii genomes offer insights to drought tolerance. The Science Researchers … feedstock with a complex genome with multiple copies of its chromosomes. Switchgrass has deep roots that allow it … several large-scale field experiments and analysis to find relationships between sequence variation and plant stress …
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Ben Bowen
… BS – University of Arkansas, Fayetteville, Chemical Engineering Ph. D. – … State University, Tempe, Chemical Engineering Post-doctoral positions – Arizona State University, Bioengineering & … 2024 Berkeley Lab Recognition of Excellence Award 2016 R&D 100 Winner 2014 Berkeley Lab …
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An Automated Tool for Assessing Virus Data Quality
… (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a … to help researchers assess and improve the quality of metagenome-assembled viral genomes . The Impact The … perform functional assessment, host prediction, and phylogenetic analysis. The development of CheckV helps …
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Data Ecosystem
… The JGI is leveraging its current partnerships to offer new capabilities and resources to users through a BER … is discoverable and accessible. Linking the resources of powerful institutions like the JGI, KBase, NCBI, NMDC, … access to diverse datasets that deepen our understanding of how organisms interact with each other and with their …
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Applying Viral Genomics Expertise to Understanding the Human Virome
… viruses outnumber the microbes by at least another order of magnitude. For years, scientists at the DOE Joint Genome Institute, a DOE Office of Science user facility located at Lawrence Berkeley … involving environmental samples to help uncover the phylogenetic diversity of the human gut microbiome. By …
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Natural Prodcast Episode 7: Ben Shen
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … say morphological, genetic, you know say sugar, lipid composition – so I think the biodiversity is probably way … see how so it’s very synergistic. BEN: So it’s a win-win proposition for both for the bigger pharmas but also for the …
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How Filamentous Fungi Sense Food
… . The Science A team led by researchers at the University of California, Berkeley used a multi-omics approach to … N. crassa is the model organism for filamentous fungi, all of which contain a wide array of plant cell-wall degrading enzymes (PCWDEs) that allow …
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2024 Progress Report
… for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … A record number of primary users — 2,456 — had active proposals with us, … processed 13,700 metabolomics samples With our users, 247 publications were published   …
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Supercharging SIP in the Fungal Hyphosphere
… The Science Researchers have successfully automated aspects of a commonly-used process for studying microbial … within a plant’s root system. They form mutually beneficial relationships with over 80% of land plants, which means they … study, due to the difficulty replicating the individual compositions of these unique communities. SIP is an effective …
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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory protein. Researchers demonstrated … associated with any particular factor. Predicting those relationships bioinformatically is almost impossible, and …
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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
…   The Science Scientists have fully decoded the genome of an oil-producing green alga, and demonstrated precise … gene targeting in the genome in the November 2025 issue of The Plant Cell. Auxenochlorella is an allodiploid hybrid … With fewer redundant pathways and clearer gene-to-function relationships than other algae, Auxenochlorella ’s reduced …
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