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… The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, … program investigates the biological mechanisms that enable fungi and algae to play a vital role in carbon cycling, … genomics research explores new metabolic processes and enzymes that can be applied in biorefineries, production of …

… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and … of Life. We then investigate the coding potential to find novel functions that may impact microbiome structure and … and complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic … monitoring, bioremediation, and the discovery of novel enzymes and bioactive compounds. …

… is a bacterial sacred metabolite, and ergot alkaloids come from fungi, and Taxol from plants. Plants, fungi, bacteria, … often use primary metabolites as building blocks to produce novel molecules. And so we’ve got glycosides being made into … And so we’ve really only come into good science for identifying secondary metabolism as we’ve sequenced more and …

… genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find … machine learning really would help distinguish and predict novel gene clusters. DAN UDWARY: Yeah, it certainly could. … some marine. There’s some soil samples. There’s human gut samples. There’s lots and lots of– animal associated, …

… you’ll be hearing about microbiology and natural products from the Great Salt Lake, and you’re going to learn, like … about natural products. So in Brad’s lab, I worked on identifying and characterizing haloperoxidases from … cool. The vanadium haloperoxidases are some really cool enzymes, and it was fun to see that project take shape. …

… DAN: Welcome back to Natural Prodcast! This is episode 4! From here on out, for a while, we’re going to be presenting … they only talk about the bacteria. My god! 30% of our gut microbes are fungi. It’s really frustrating to me. Maybe … I wish we could predict. I wish we could look at these enzymes and predict, and really place it to structure. …

… Our homepage video includes external footage from: University of Delaware; Laura.Selbmann©PNRA. All the … of University and Research; all specimens collected and fungi isolated are preserved in the Culture Collection of Fungi from Extreme Environment, the Italian National …

… Fungi from herbivore poop make surprisingly complex compounds — an … feat thought to be too costly for them. The Science Anaerobic fungi, which die in the presence of oxygen, dwell … work shows that anaerobic fungi might be a new source of novel compounds to help bolster the bioeconomy. Summary A …

… genomics with metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables … molecules function within plants, microbes, and ecosystems. Identifying and analyzing primary and secondary metabolites … mass spectrometry-based methods to analyze metabolites from a wide range of biological and environmental samples — …

… the University of Hawaii and moved there in the early ’60s from Berkeley to work on this new budding field of marine … might make this molecule and predicting what kind of enzymes might be involved, and then being able to make those … cool because the work has gone so much more than just identifying genes to that toxin, but it’s opened up this …

… Prodcast. And it’s our conversation with Nadine Ziemert from the University of Tübingen in Germany. Like me, she’s a … And then you search for – re-search for these biosynthetic enzymes that we think must be similar within the fosmid … of the soil, because there’s no secondary metabolites from anaerobic bacteria– something we know now is actually not …