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… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of … of interest. One such effort is targeted at environmental cells that are from candidate phyla, major branches in the phylogenetic … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the efforts … is done in a timely fashion. The publications resulting from such efforts should specify the collaborative nature of …

… for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in ongoing …

… automation — and further advancing sequence applications, single cell genomics, biodesign, and metabolomics … profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a … DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling …

… proposals within the focused topic areas that can be completed on an accelerated timeline as compared with the … provides customized analysis, the JGI also participates in publication of results. … staff of the participating User Facilities, as well as DOE. Nearly all LOIs are accepted for full proposal submission, …

… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in … We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning … discovering and characterizing giant viruses, which possess genomes and particle sizes that rival those of cellular …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with individual cells. Research Team    … DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling …

… of bacteria and archaea in their natural environments using single cell approaches. This includes linking strain-level genetic variation to ecological niche adaptations.  Single cell sequencing approaches are also used … The program also collaborates with isolate collections to complete large-scale sequencing projects, including 10,000 …

… the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw … sequence data to  SRA at NCBI once the standard analysis is complete. Raw metabolomics data is submitted to the  MassIVE … and quality of finished product depend on genome. Selected genomes will be improved based on feasibility and scientific …

… things off this time around, talking about a subject that’s near and dear to my heart. And that is, we wanted to do a … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … what looked to be novel biosynthetic gene clusters, like completely new things that we haven’t seen before. And so …