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… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to produce manuscripts for publication and the responsibility for leading the efforts … (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any …

Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … of secondary metabolites and improving the tools for their characterization, the program strives to facilitate the discovery of new bio-based molecules that can drive …

… research in synthetic biology, the program enables the design and synthesis of complex genetic pathways and … to explore sequence-function relationships, advancing the discovery of new biosensors for biofuels and bioproducts. … requiring cycles of construct design, building, and characterization. In partnership with the Joint BioEnergy …

Bill Gerwick as part of the International Biodiversity Drug Discovery consortium doing natural products … of sort of cooperative and collaborative science. It was designed to ensure equitable benefit sharing if any … the really early work – it took a long time for .. I mean, structural elucidation was extremely difficult before the …

Our research is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic … and biogeochemical cycles. Research Team    … A complete publication list available at Google Scholar. Schulz, C …

… in that. And we have a project working on pain drug discovery from those animals. A second area that I’m really interested in is how to use design principles to make new compounds. And that’s related … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This opportunity, provided … to perform computational analysis. IMG/M user interface is designed for use by microbiologists to quickly bridge the …

… with their target. And so, for example, you could think of designing one of those that can trick an enzyme into … lab now is use these as a resource for natural product discovery because we can genetically manipulate them. I … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … a chemical history. So it is not an easy one, obviously, to design an experiment rather than just going for evidence on … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS … briefly describing the project motivation, experimental design, capabilities to be used and DOE mission relevance. … available at Oak Ridge National Laboratory  Center for Structural Molecular Biology . … Accessing NEON’s …

… always been the main driver for secondary metabolism drug discovery. Because we always need new antibiotics. We need … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … NRPS A domains. (Dan’s favorite review on NRPS structural biology is here ) And so we talked about …