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Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of … such effort is targeted at environmental cells that are from candidate phyla, major branches in the phylogenetic … in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with individual cells. Research Team    … The JGI uniquely offers the first …

… the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw … sequence data to  SRA at NCBI once the standard analysis is complete. Raw metabolomics data is submitted to the  MassIVE … and quality of finished product depend on genome. Selected genomes will be improved based on feasibility and scientific …

… proposals within the focused topic areas that can be completed on an accelerated timeline as compared with the … FICUS call with EMSL begin with a Letter of Intent (LOI) from a researcher, briefly describing the project … Accessing Resources at Multiple DOE User Facilities with a Single Proposal describes the resources available from the …

… data and serving them to users via the Integrated Microbial Genomes & Microbiomes (IMG/M) system. Research Team    … The … nearly 18% of all existing species. Additionally, the complete linkage clustering made it possible to confidently … species specificity of single cells and genomes extracted from metagenomes, and also as a metric for quality control …

This time, we’ve got a great interview with Ben Shen, from the Scripps Research Institute in Jupiter Florida. This … well. One is to do DNA sequencing. So upon sequencing many genomes, now we don’t have to, as in the past, go randomly … natural product producing organism, the Actinomyces, was completed in early 2000s. One of the major discovery from …

The program also collaborates with isolate collections to complete large-scale sequencing projects, including 10,000 … catalog : Beyond minimal draft and improved draft microbial genomes the program offers single-cell sequencing, … of sequence space:  The JGI generates reference genomes from diverse bacterial and archaeal lineages to improve …

… our interview this week is with Professor Brian Bachmann from Vanderbilt University’s Chemistry Department, where he … called Ecopia was talking about a gene cluster a week. They completed a gene cluster per week. And that really got me … come, though, too when you start talking about going after single gene clusters. BRIAN BACHMANN: That’s right. JACKIE …

… for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with … Joint Genome Institute, builds upon thousands of microbial genomes that have been sequenced by the JGI though not … … A primary purpose of this project is to bring educators from a broad range of disciplines up-to-speed with some of …

I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find … what looked to be novel biosynthetic gene clusters, like completely new things that we haven’t seen before. And so …

Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … regulation, and noncoding RNAs in microbiomes. The insights from this work have the potential to drive innovations in … assembly and binning have enabled reconstruction of complete or near-complete population genomes directly from …

… is a bacterial sacred metabolite, and ergot alkaloids come from fungi, and Taxol from plants. Plants, fungi, bacteria, … and you can see that different Frankia have different size genomes depending on what kinds of plants, and what kinds of … think of bacteria. You think of bacteria as sort of these single celled organisms, kind of all over. But these kinds …