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Natural Prodcast Episode 4: Nancy Keller
… teach microbiology – “microbiology” – it’s almost 95% bacteria! What happened to all the other microbes? So … I don’t know, is 30 megabases? Basidiomyetes might get to 50. Some of them go to over 100. There. That can be the … is it a parasitic to?   NANCY: Humans. It causes – it’s terrible – it’s mostly in Africa. You get severe diarrhea, …
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Does time matter? Intraspecific diversity of ribosomal RNA genes in lineages of the allopolyploid model grass Brachypodium hybridum with different evolutionary ages
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The Expanding Universe of Methane Metabolisms in Archaea
… available metagenome data provided by the other study co-authors, and reconstructed from these 10 … oldest metabolisms, with the first traces possibly at ~3.5 Gy (billion years),” Borrel and Gribaldo said in an email. … to Korarchaeota Drs. Luke McKay and William Inskeep are co-authors on the Borrel et al. study described above, and also …
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Natural Prodcast Episode 7: Ben Shen
… because they’re so reactive. BEN: …going back to the 1950s. But the structure of which was not known until the … different people have different numbers, but in general, an authoritative number for total number of natural products of … among the 70,000 microbial natural products total, about 500 drugs have been out of these natural products. So this …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… publicly available for the research community,” says lead author Serina Robinson, a postdoctoral fellow at the ETH …
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A Sorghum Pangenome Opens More Doors to Discovery
… and a member of the JGI Plant Program. Lovell was a senior author on this work with Nadia Shakoor, a research scientist … global crop trait discovery.  Nature (2026). doi:10.1038/s41586-026-10229-9   …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… out where I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. … Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in … in this kind of a vein. We sequenced in the end about 150,000 genomes, just to look for a very specific class of …
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JGIota: Looking Back at How Cow Rumen Samples Landed on a Syllabus
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of … National Laboratory researchers were studying Chromosome 5, which contains about 6% of the human genome . They … the human genome, an arms race was being waged. In the JGI@25 video below, Susan Lucas, former JGI Production Department …
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JGI Announces 2023 Community Science Program Awardees
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A Collaboration to Improve Plant Genome Annotations Across Species
… Gene Atlas in  Nucleic Acids Research . The project spans 15 years and involves more than 17 research groups. The team … Manager Sarah Sharman recently interviewed study first author Avinash Sreedasyam, a HudsonAlpha senior scientist, … targets for plant improvement. Surprisingly, about 16 to 56 percent of plant genes are poorly characterized, meaning …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… $19 to make, and it could be sold in the United States for $50-200, generating a potential profit of $1.4 million … Department of Energy operated under Contract No. DE-AC02-05CH11231. Work at the Molecular Foundry was supported by the … the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. This research was developed with funding from the …
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