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Tanja Woyke Elected to American Academy of Microbiology
… of Microbiology (AAM) ! She is among the 68 new Fellows in the Class of 2020, selected from 118 nominees. The selection process for AAM Fellows is based on their records of scientific achievement and original contributions that have advanced microbiology. Academy …
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Streamlining Regulon Identification in Bacteria
… RIViT-seq technology could speed up associating transcription factors with their target genes. The … that can be turned on or off by the same regulatory protein. Researchers demonstrated the efficacy and potential of … transcription. Summary Transcription in eukaryotes is handled by three distinct RNA polymerases; in bacteria there …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… warm-adapted microbes edge polewards, they’d oust resident tiny algae. The cold polar oceans give rise to some of the … their base are microscopic, photosynthetic algae. But human-induced climate change , a new study suggests, is displacing these important cold-water communities of algae with …
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Mindfully Moving JGI
… JGI is in the process of shifting its operations from Walnut Creek to the heart of the … Lab campus. By Friday, October 18, the production sequencing labs in Building 100 were silent. Twenty years after the … in the physical sciences in the United States, and is working to address some of the most pressing challenges of …
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2024 Progress Report
… The Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems … who made use of our data. We completed 39,870 projects in FY24 We generated 871 Terabases of sequence We … advanced genomic capabilities. This year we brought online the latest short-read technology, the Illumina NovaSeq X …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring multiple omics methods to examine microbial chemical production. The Science Soil bacteria … This work conducted by the U.S. Department of Energy Joint Genome Institute (https://ror.org/04xm1d337), a DOE …
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… Sequencing technology has changed dramatically over the last  25-plus years since the JGI’s inception, making it possible for researchers … JGI and Berkeley Lab were developing specific programs to handle this scale of data. Part 2: Souped Up Computing — … in the physical sciences in the United States, and is working to address some of the most pressing challenges of …
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JGI Workshops at PAG
… Jan. 12 workshop: The Rapidly Expanding Genomics of Algae   With advances in genomics technologies, keen interest in the bioenergy and biotechnology potential of …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… Trained on environmental data, a new JGI tool more accurately facilitates microbial genome discoveries. Unlocking the intricate details of life’s genetic blueprint has … scale with 4 billion parameters is not a task that can be handled by a small computer cluster. GenomeOcean was trained …
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An Enzyme System to Help Catalyze Bioproduction of Plastic
… By characterizing the structure and function of a methylthio-alkane … reductase system, researchers could open avenues for using bacteria to produce ethylene and more.  Microbes excel at recycling the abundant miscellanea of their surroundings. Case in … in the physical sciences in the United States, and is working to address some of the most pressing challenges of …
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Help from Citrus’ Bitter, Hardier Cousin
… to disease-resistance that could prove fruitful for saving Citrus from greening disease. You’ve probably never heard of trifoliate … known as  Poncirus trifoliata , it’s an evolutionary cousin of the  Citrus genus, which gives us lemons, kumquats, … in the physical sciences in the United States, and is working to address some of the most pressing challenges of …
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The Expanding Universe of Methane Metabolisms in Archaea
… Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse gas 20 … than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key role in determining the … in the physical sciences in the United States, and is working to address some of the most pressing challenges of …
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