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The Megadata of Lake Mendota - Part 1: Many, Many Mers
… Lake Mendota sits right next to the University of Wisconsin, Madison. And Trina McMahon's lab has been sampling the microbes … together.  The next 3 episodes are the story behind that giant assembly from Lake Mendota. In this episode: the …
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Microbial Genomics & Metagenomics (MGM) Workshop
… Registration has closed.  The U.S. Department of Energy (DOE) Joint … Genome Institute (JGI) is offering a five-day workshop on Microbial Genomics and Metagenomics. Details: … Genomes & Microbiomes (IMG/M) data and workflows for computational analysis and interpretation of sequence data. …
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Mike Sneddon
… Dr. Sneddon is the Advanced Analysis Group Lead in the Data Science … engineers and scientists builds and operates the data and compute platforms and bioinformatics annotation pipelines that support JGI’s portals, tools, and the … S., Pelikan, C., Scannell, D., Serber, Z., Shock, J., Sneddon, M., and Yang, X. Metagenomic library and natural product …
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The Megadata of Lake Mendota - Part 2: Souped Up Computing
… This series is the story of a giant metagenome assembly from Wisconsin’s Lake Mendota. In this episode: a look at the supercomputing that stitches together large datasets with the …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring … factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under standard conditions. As described in a recent … This work conducted by the U.S. Department of Energy Joint Genome …
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2025 Progress Report
… JGI researchers demonstrate how their laboratory and data science efforts … discoveries. (Pictured from left to right: Peng Wang, Sravanthi Tejomurthula, Mi Yan, Deanna Beatty)    Vision  Lead … and professional expertise to support the global research community in studies of complex biological and environmental …
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Evolution of a Fungal Gene Expression Regulator
… analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or G in a … its carbon ring, or 5mC. In many organisms, 5mC is an important piece of how they regulate their genomes, but is not … abundance of fungal genomes underscores the need for a more comprehensive exploration of genomic DNA modifications …
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JGI-UC Merced Interns Share Their 2021 Experiences
… JGI mentors to investigate rigorous research projects, hone science presentation skills, and participate in professional development enrichment activities. For some students in … Evolution of the Mitochondria Internship … Cross Species Integration of Single Cell Transcriptomes …
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Mapping Heat Resistance in Yeasts
… A new approach for improving functional annotation in fungal genomes. The Science In a … given species. These approaches don’t allow researchers to compare across very distant species that no longer mate to produce progeny. The … The work conducted by the US Department of Energy Joint Genome …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… deep subsurface ecosystem. The Science Altiarchaea are carbon-fixing microbes and targets of multiple viruses in Earth’s deep subsurface. They are abundant representatives of deep subsurface ecosystems. A team of … battle waged below the Earth’s surface is reconstructed by combining a study of microbial communities (metagenomics) …
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How Filamentous Fungi Sense Food
… of California, Berkeley used a multi-omics approach to reconstruct and model gene regulatory pathways used by the … and decide on the order in which this fungus breaks down plant cell wall materials including lignin, cellulose and … them to efficiently break down the wide array of simple and complex components present in plant biomass. This is of …
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New and Improved: Eucalyptus Reference is Now Accessible
… assembly to support targeted tree breeding for the bioeconomy.   The Science Researchers report a new reference … of the journal G3 Genes | Genomes | Genetics , with significant advances compared to the 2014 Eucalyptus grandis reference genome … WIP proposal ID: 508017, Myburg, Wegrzyn, Borevitz) conducted by the US Department of Energy Joint Genome …
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