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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… With a new methodology, scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … it’s difficult to link the connections to them from the genetic elements that scientists have found, e.g. plasmids …
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Ian Blaby
… Since 2019 Dr. Blaby heads the Biodesign Platform at the … National Laboratory where he focused on functional genomics of phototrophs. Through this and post-doctoral positions at University of Florida and UCLA he has worked with a wide range of … B.Sc. (HONS) – University of Wales, Cardiff, Genetics Ph.D. – University of …
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The Power of One, Amplified
… A preview of how large-scale single cell genomics complements metagenomics studies. The … that species specific sets of single cells harbored mobile genetic elements that were missed within paired metagenome … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Toasting to the 2020 JGI-UC Merced Summer Internship Program
… UC Merced students and their JGI mentors toasted to the end of a nine-week virtual internship. The celebration was preceded by … JGI staff. According to Axel Visel and Zhong Wang, founders of this internship program, this was the largest turnout for …
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2024 Progress Report
… The Integrative Genomics Building (IGB) seen above is home to … for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … processed 13,700 metabolomics samples With our users, 247 publications were published   …
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Katherine Louie
… Dr. Louie joined the JGI in 2014 to develop the metabolomics program, … efforts to expand the metabolomics capabilities and product offerings for JGI users.  Using cutting-edge mass … techniques, the platform delivers rich metabolite profiles from diverse biological and environmental samples in …
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Extracting the Secrets of Secondary Metabolites
… for survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … is a technique researchers can use to integrate large genetic payloads directly into diverse microbes. Combining … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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How Maize Makes An Antibiotic Cocktail
… Maize produces a family of compounds that protects it against infections — using surprisingly few enzymes. The … They screened panels of hundreds of maize lines for genetic variation in the ability make zealexins, and … sesquiterpenoids, National Science Foundation Plant-Biotic Interactions Program (grant no. 1758976 to E.S. and P.Z.) …
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Virus Discoveries that Keep Getting Bigger
… Sequence-based studies — from metagenomics to single-cell work — have quickly accelerated understanding of giant viruses. The Science In the last thirty years, in … methods, researchers have shed light on the genetic makeup of new giant viruses. This review highlights …
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Secrets of the Needles: What Microbes do on Conifer Leaves
… Novel study looks at microbiomes in aerial surfaces of plants and their roles in plant health … Robert Bowers . She contributed to the analysis of mobile genetic elements across all of the metagenomes. Learn more … ) conducted by the U.S. Department of Energy Joint Genome Institute ( https://ror.org/04xm1d337 …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users … Streptomyces are nature's chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under … This work conducted by the U.S. Department of Energy Joint Genome Institute …
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Ben Bowen
… Specializing in mass spectrometry-centered projects, Dr. Bowen’s work focuses on developing high-performance computing workflows and integrating mathematics and chemistry for … BS – University of Arkansas, Fayetteville, Chemical Engineering Ph. D. – Arizona State University, Tempe, Chemical …
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