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Fishing for Novel Cellulose Degraders
… genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is a boxful of lures. Designed with feathers or wires to mimic an insect … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Viruses Reprogram Cells into Different Virocells
… from The Ohio State University and the University of Michigan studying how virus infections cause significant … metabolic changes they’ve undergone. The Impact The number of microbes in, on, and around the planet is an astronomical … viruses outnumber surface microbes 10 to 1, and 20% to 40% of the microbes are infected at any given time. Microbial …
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DAS Tool for Genome Reconstruction from Metagenomes
… been utilizing metagenomics as a way to study a collection of hard-to-culture microbes, but the efficacy of this approach would be greatly increased by having the ability to reconstruct complete genomes of individual, unknown microbes in the community. Since the …
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Extracting the Secrets of Secondary Metabolites
… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … effectiveness has historically been limited due to the lack of robust tools available for carrying CRISPR into … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… di-GMP (Guanine Monophosphate) is found in nearly all types of bacteria and interacts with cell signaling networks that … role in regulating microbial cellulose production and biofilm formation, which affects a number of environments, including plants, soil, and the gut. To …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… A special issue of Synthetic Biology celebrates research enabled by the JGI … and synthesis work. This is where the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … more than 10 papers, including two Nature Plants publications, in five years, have come out of the …
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The JGI announces 2024 awardees for our Community Science Program annual call
… Annual Call. “It’s exciting to see the diverse portfolio of successful CSP proposals this year,” noted Tanja Woyke, … large-scale genomic science projects relevant to the DOE’s Office of Biological and Environmental Research (BER) missions in: …
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Hiroshi Otani
… technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo PhD, Biotechnology, University of Tokyo … Udwary DW, Mouncey NJ. Comparative and pangenomic analysis of the genus Streptomyces. Sci Rep. 2022 Nov 7;12(1):18909. …
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Katherine Louie
… efforts to expand the metabolomics capabilities and product offerings for JGI users.  Using cutting-edge mass … techniques, the platform delivers rich metabolite profiles from diverse biological and environmental samples in support of user science.  Capabilities offered by the platform are a …
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Mike Sneddon
… Department at the Joint Genome Institute. His team of engineers and scientists builds and operates the data and … science.  Dr. Sneddon is an accomplished leader in data, software, compute, and AI for large-scale genomics and lab … Prior to joining JGI in late 2025, he served as Director of Scientific Computing at Predicine, an NGS-based clinical …
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Benjamin Cole
… University of California, San Diego (PhD, 2011) Rensselaer Polytechnic … List of pubs available on NCBI … Implementation of the Index of Cell Identity as an R package … Selected Publications … Software …
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Igor Grigoriev
… at Lawrence Berkeley National Laboratory, and an Adjunct Professor of Plant and Microbial Biology at University of California, Berkeley. He contributed to the Human Genome … at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.  …
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