Igor Grigoriev | Joint Genome Institute

Fungal & Algal Program Head

Fungal + Algal Program

Dr. Grigoriev joined the DOE Joint Genome Institute in 2003, following his postdoctoral training at UC Berkeley and work in the pharmaceutical industry. He holds joint appointments as Fungal and Algal Program Head at the DOE Joint Genome Institute, a Senior Scientist at Lawrence Berkeley National Laboratory, and an Adjunct Professor of Plant and Microbial Biology at University of California, Berkeley. He contributed to the Human Genome Project and led annotation and analysis of diverse eukaryotic genomes, from protists to plants. In 2009, he launched the JGI Fungal Genomics program which resulted in over 2500 fungal genomes in the JGI MycoCosm portal. In 2018, he launched scale-up of algal genomics and PhycoCosm portal. Dr. Grigoriev engaged thousands of researchers in genome projects and organized numerous genomics workshops.

Education

Selected Publications

Lankiewicz et al (2023) Lignin deconstruction by anaerobic fungi. Nature Microbiol. 8(4):596-610.
Nelson et al (2022) Wildfire-dependent changes in soil microbiome diversity and function. Nature Microbiol. 7(9):1419-1430.
Ye et al (2022) The role of zinc in the adaptive evolution of polar phytoplankton. Nature Ecol Evol. 6(7):965-978.
Grigoriev et al (2021) PhycoCosm, a comparative algal genomics resource. Nucleic Acids Res. 49(D1):D1004-D1011
Swift et al (2021) Anaerobic gut fungi are an untapped reservoir of natural products. Proc Natl Acad Sci U S A. 118(18):e2019855118.
Miyauchi et al (2020) Large-scale genome sequencing of mycorrhizal fungi provides insights into the early evolution of symbiotic traits. Nature Commun. 11(1):5125.
Krizsán et al (2019) Transcriptomic atlas of mushroom development reveals conserved genes behind complex multicellularity in fungi. Proc Natl Acad Sci U S A. 116(15):7409-7418.
Varga et al (2019) Megaphylogeny resolves global patterns of mushroom evolution. Nature Ecol Evol. 3(4):668-678.
Ahrendt et al (2018) Leveraging single-cell genomics to expand the fungal tree of life. Nature Microbiol. 3(12):1417-1428.
Haitjema et al (2017) A parts list for fungal cellulosomes revealed by comparative genomics. Nature Microbio 2:17087.
Mondo et al (2017) Widespread adenine N6-methylation of active genes in fungi. Nature Genet. 49(6):964-968.
Mock et al (2017) Evolutionary genomics of the cold-adapted diatom Fragilariopsis cylindrus. Nature. 541(7638):536-540.
Riley et al (2016) Comparative genomics of biotechnologically important yeasts. Proc Natl Acad Sci U S A. 113(35):9882-7.
Kohler et al (2015) Convergent losses of decay mechanisms and rapid turnover of symbiosis genes in mycorrhizal mutualists. Nature Genet. 47(4):410-415.
Grigoriev et al (2014) MycoCosm portal: gearing up for 1000 fungal genomes. Nucleic Acids Res.42(1):D699-704.
Read B et al. Pan genome of the phytoplankton Emiliania underpins its global distribution. Nature. 2013; 499: 209-213.
Curtis BA Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs. Nature. 2012; 492: 59-65.
Floudas D et al. The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes. Science. 2012;336: 1715-1719.
Berka RM et al. Comparative genomic analysis of the thermophilic biomass-degrading fungi Myceliophthora thermophila and Thielavia terrestris. Nat Biotechnol. 2011; 29: 922-927.
Eastwood DC et al. The plant cell wall-decomposing machinery underlies the functional diversity of forest fungi. Science. 2011; 333: 762-765.
Gobler CJ et al. Niche of harmful alga Aureococcus anophagefferens revealed through ecogenomics. Proc Natl Acad Sci U S A. 2011; 108: 4352-4357.
Banks JA et al. The Selaginella Genome Identifies Genetic Changes Associated with the Evolution of Vascular Plants. Science, 2011; 332: 960-963.
Colbourne JK et al. The ecoresponsive genome of Daphnia pulex. Science. 2011; 331: 555-561.
Ohm RA et al. Formation of mushrooms and lignocellulose degradation encoded in the genome sequence of Schizophyllum commune. Nat Biotech. 2010; 28: 957-963.
Worden AZ et al. Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas. Science. 2009; 324: 268-272.
Bowler C et al. The Phaeodactylum genome reveals the dynamic nature and multi-lineage evolutionary history of diatom genomes. Nature. 2008; 456: 239-244.
Martin F et al. The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis. Nature. 2008; 452: 88-92.

Awards and Service

two microscopic images, one of fungi and the other of algae

Fungal & Algal Science Program

Igor Grigoriev is the Fungal & Algal Science Program Head at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.

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