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The More the Merrier: Making the Case for Plant Pan-genomes
… system traces polyploid genome evolution. Flowering plants abide by the concept, “the more the merrier,” with respect to their genomes. In their base state, they are diploids with two genome copies, one from each parent. Having three or more genome copies from additional parents or …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements … of the tree of life. Used in tandem over the years, metagenomics and single cell genomics have afforded JGI …
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An Integrated Dataset to Understand Ecosystem Interaction
… yields a comprehensive tree and soil dataset for understanding the dynamic relationship between poplar trees and their … processes for the first time. By collecting data from 27 different poplar ( Populus trichocarpa ) trees, as well … managed through human intervention. By leveraging metagenomics, scientists were able to analyze the DNA of …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… Meta-omics datasets show that CRISPR-Cas systems determine mutualism or parasitism between some archaeal hosts and their hitchhikers. The Science Within the archaeal domain, there is a group of tiny … symbiotic interactions are difficult to study in the lab. Metagenomics provides new views of these relationships.  …
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Fungal Friends or Foes in Plant Roots
… Uncovering associations between plant roots and fungi that can help … analysis identified fungal gene families that help determine if these fungi act as friends or foes. The Impact … communities comprised of fungi and bacteria can thrive in plant roots. They play key roles in maintaining the …
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Three Join the JGI User Executive Committee
… of the University of California, Santa Barbara. They join eight other JGI users already serving on the UEC – go … CSP and the JGI-EMSL FICUS programs and brings expertise in metagenomics and novel applications for long-read DNA … Greenham stepped down at the end of her term. In late 2023, the JGI launched a solicitation for nominations for …
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Dan Rokhsar
… Dr. Rokhsar joined the JGI in 2000 as the founding Associate Director for Computational … group, and is past lead of the Eukaryotic Genome Program (2010-2019), and JGI Chief Informatics Officer (2013-2016). … AB in Physics, Princeton University, NJ MS in Theoretical …
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Soil virus offers insight into maintaining microorganisms
… Using the IMG/M data portal, researchers have identified a … impact on the microbial communities within soil. Using metagenomics, scientists can shed light on hidden … domains of life.  Using the IMG suite, JGI retrieved 142 of the GH75 AMGs, which encode enzymes that break down …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… diversity of large and giant viruses. While the microbes in a single drop of water could outnumber a small city’s … been co-cultivated with amoeba or with their hosts, though metagenomics is now making it possible to seek out and characterize uncultivated viruses. For instance, a 2018 study from a JGI-led team uncovered giant viruses in …
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2024 Progress Report
… The Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome … in our new Strategic Plan , which was released in April 2024 — through serving an increased number of users with a … processed 13,700 metabolomics samples With our users, 247 publications were published   …
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Applying Viral Genomics Expertise to Understanding the Human Virome
… tools and data hub for NIH program. While the microbes in, on and around Earth outnumber the stars in the Milky … metagenome-assembled viral genomes ( Nature Biotechnology , 2021), geNomad , a tool for identifying mobile genetic … (“contigs”) from thousands of ecologically diverse metagenomics samples. The work is supported by NIH Common …
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Picking Up Threads of Cotton Genomics
… Analysis reveals cotton genome stability across global lineages . Come harvest time, the cotton fields look like … All of these cotton lineages have genomes approximately 2.3 billion bases or Gigabases (Gb) in size, and are hybrids … Science “The results described in this  Nature Genetics publication will facilitate deeper understanding of cotton …
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