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Applying Viral Genomics Expertise to Understanding the Human Virome
… viruses outnumber the microbes by at least another order of magnitude. For years, scientists at the DOE Joint Genome … analytics for uncovering virus dynamics and functional potential ," is among the five focused on tool development. … (“contigs”) from thousands of ecologically diverse metagenomics samples. The work is supported by NIH Common …
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Biotech Partners Summer Intern Co-Authors NAR Paper
… Kaushal Sharma, one of five Antioch High School rising juniors who participated … internships at the DOE Joint Genome Institute this summer through the Biotech Partners program is now an author on a Nucleic Acids Research publication. The paper describes the version 6 data updates …
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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing … cell’s membrane. Two decades ago, a team discovered a group of viruses that had in their genomes a surprising tool: a … genomes. That means that those viruses accessed many more potential microbial cells or hosts. This ability isn’t …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… hydroxyapatite, a high-value biomaterial with a wide range of industrial applications. The team was led by researchers … chemicals that could also be produced from urine while also potentially reducing the typical energy production costs … care, plastic surgery and even archeological restoration. Through a Laboratory-Directed Research and Development …
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DOE JGI Metagenome Workflow
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Terabase-scale metagenome coassembly with MetaHipMer
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ClaMS: A Classifier for Metagenomic Sequences
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Doubling Down on Known Protein Families
… online Oct. 11, 2023 in  Nature highlights the vast array of functional diversity of microbes through a novel approach to better understand microbial … insights, significantly expanding the horizons of potential functions across various categories of proteins, …
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Engagement Webinar: Harnessing JGI’s Metabolomics Capabilities
… spotlighted the metabolomic analysis capability available through the  Community Science Program (CSP) . This includes mass spectrometry-based measurements of primary and secondary metabolites from plants, … apply for CSP?  I am at NIST. A: The JGI User Programs are designed to be available to academic, government agency, …
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Hiroshi Otani
… technologies and methodologies that facilitate discovery of new secondary metabolites. Prior to joining the JGI, he … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo PhD, Biotechnology, University of Tokyo … Udwary DW, Mouncey NJ. Comparative and pangenomic analysis of the genus Streptomyces. Sci Rep. 2022 Nov 7;12(1):18909. …
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JGI Early Career Researchers Featured in mSystems Special Issue
… In a special issue of mSystems , out May 14, 2019, JGI researchers are among … beyond the tried-and-true method of traditional shotgun metagenomics. One approach uses fluorescence-activated cell … be the foundation upon which researchers can develop high-throughput and high-resolution studies of interactions …
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2024 Progress Report
… for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … systems. We optimize our service to the community through responsibly managing our people and resources.     … processed 13,700 metabolomics samples With our users, 247 publications were published   …
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