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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… like plasmids, the picture is far from complete.  In 2021 , scientists at St. Jude Children’s Research Hospital … Office of Science of the U.S. Department of Energy [DE-AC02-05CH11231]. Dr. Charles Gawad has been supported for this …
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Microbiome Data Science Team
… the global diversity of alternative genetic codes (Science 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science 2017, Nature Microbiology 2018), discovery of new genes with … dark matter through global metagenomics. Nature . 622(7983):594-602. Camargo AP. et al. (2023) Identification of mobile …
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New Vision, New Mission, New Plan: The JGI’s Next Five Years
… New 5-year strategic plan outlines how the JGI will advance the … (DOE) Joint Genome Institute (JGI) has released its newest 5-Year Strategic Plan: Innovating Genomics to Serve the Changing Planet (download a copy at jointgeno.me/2024StrategicPlan .) This plan aligns the DOE Office of …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… $19 to make, and it could be sold in the United States for $50-200, generating a potential profit of $1.4 million … U.S. Department of Energy operated under Contract No. DE-AC02-05CH11231. Work at the Molecular Foundry was supported by the …
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Mining Public Databases Yields Largest Map of Fungal Mitochondrial Genomes to Date
… dataset of its kind ever assembled. The team identified 15 core genes shared across all fungi, and found that some of … gene models. The JGI workflow consistently recovered all 15 core mitochondrial genes across the dataset, whereas a … size and structure varied enormously, ranging from just 12 kilobases in Rozella allomycis , an early-diverging …
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Crysten Blaby-Haas
… Dr. Blaby-Haas joined the JGI in 2022 as lead of the Biomolecular Materials Initiative, a … reverse genetics to test those hypotheses. From 2011 – 2015, she worked with Sabeeha Merchant at UCLA as a NIH Ruth L. … research career at Brookhaven National Laboratory (2015) where she co-founded and led the Quantitative Plant …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… to stress. The Impact Despite constituting less than 5% of land on Earth, peatlands store approximately one-third … peat from these boggy wetlands produces an estimated 5% of annual greenhouse gas emissions. Understanding how … a genus of just under 400 mosses that can carry up to 25 times their dry weight in water, makes up the …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… of Energy Joint Genome Institute (https://ror.org/04xm1d337), a DOE Office of Science User Facility, is … U.S. Department of Energy operated under Contract No. DE-AC02-05CH11231. …
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A Community Resource for Secondary Metabolite Researchers
… of Energy Joint Genome Institute (https:// ror.org/04xm1d337), a DOE Office of Science User Facility, is … Office of Science of the U.S. Department of Energy [DE-AC02-05CH11231]. …
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Secrets of the Needles: What Microbes do on Conifer Leaves
… summer project in the JGI-UC Merced Internship Program. In 2023, Shayna Bennett, a UC Merced graduate student in Carolin … by the National Science Foundation (NSF) under grant DEB-1442348. The work (proposal:  https://doi.org/10.46936/10.25585/60000936 ) conducted by the U.S. Department of Energy …
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iPHoP: A Matchmaker for Phages and their Hosts
… pairs to generate a matrix of data points.  Applied to 216,015 high-quality virus sequences in the IMG/VR database, the … Research Program awarded under UC-DOE Prime Contract DE-AC02-05CH11231. The work conducted by the U.S. Department of …
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