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… and scientists of secondary metabolism.  DAN: Hey there and welcome back for Episode 8 of Natural Prodcast. This week, … can use peptides for! That’s what his collaboration with JGI is all about, and we talk about it a bit here. I have … because it was too long. Well, when we went looking for a photo of John, we found one from the 70s in the Scripps …

Doering and Bryce Foster and too many others to name at JGI for the last two years or so. SMC is now released and … to a molecule that’s actually helping people and being beneficial in terms of medicine. And that’s something we … of Utah , about her secondary metabolism research on novel microbes and bioactive compounds in the Great Salt Lake. …

The JGI’s Microbial Program focuses on using cutting-edge … techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those … addressing key environmental challenges, such as improving soil health, carbon sequestration and bioeconomy …

The JGI has a strong interest in seeing that the data produced by the facility result in scientific publications. JGI users … for leading the efforts to do so, and JGI expects acknowledgment (see Auspice Statement below) for the generation …

… approaches to unravel functional capabilities of plants, microbes and microbial communities, global carbon and … of Biological and Environmental Research (BER) missions .  While applications will be accepted that address any aspect … that are listed in the call and leverage the diversity of JGI technical and analytical capabilities. All proposals …

Metabolomics strengthens -omics technologies at the JGI by identifying the actual molecules present in an … variety of experimental samples, including organisms (e.g. microbes, fungi, plant), media in which they grow, as well as different types of environments (e.g. soil, lake).  A wide range of metabolites are identified …

… activity. So the chemistry and function really of those microbes that live there.  And in our work we’ve determined … bacteria there is more horizontal transfer. And so it’s beneficial then to have secondary metabolism in proximity … do when you’re exploring your systems. Because I think the JGI has a little bit of a different approach. We don’t …

… we talk about my favorite topic in, arguably, my area of expertise, which is genome mining. You’ll hear us talk about … to the California gold rush. And we’ll talk about a new JGI paper that’s just come out where I got the chance to do … disparate environments. There’s some marine. There’s some soil samples. There’s human gut samples. There’s lots and …

… recorded at the SIMB Natural Products conference, which took place last January 2020 in San Diego. San Diego, … systems. No one was, at that time, really working with microbes from the ocean. So I felt there was a wonderful … first genome sequence with you. Brad: That’s right,  Dan: JGI did it in fact. Brad: That was a magical project I …

At the end of the day, all the content produced by microbes the result of millions of years of evolution. And … because otherwise it will be targeting a target that is not beneficial anymore, and instead of being a nice antibiotic … thing. Another way to approach it is more related to what JGI does, which is sequence genomes. And we just published …

… product reports on the evolution of genome mining and microbes with Mohammad Alanjary and Tilmann Weber to be a … was fascinating, I think. DAN UDWARY: Yeah, and that was a JGI Community Sequencing Project. You’re right, yeah. NADINE … of these environments? NADINE ZIEMERT: So we started with soil. But we also have, in collaboration with other people, …

JGI researchers lend expertise to develop tools and data hub for NIH program. While the microbes in, on and around Earth outnumber the stars in the …