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Trent Northen
… the ENIGMA SFA project. In 2015, he founded what is now the JGI Metabolomics Program to provide advanced metabolomic … Commun. 2019 10(1):2770. doi: 10.1038/s41467-019-10542-0. Wang G et al. Chassis-Independent Recombinase-Assisted … Engineering Enables Rapid Activation of Biosynthetic Gene Clusters. Nat Microbiol. 4(12):2498-2510. doi: …
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Boosting Small Molecule Production in Super “Soup”
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … The work started with yeast strains engineered by Alper’s team to convert the sugar glucose to the products including … of the yeast’s native glucose metabolism Alper’s graduate student Xiunan Yi visited the Jewett lab to provide a …
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An Integrated Dataset to Understand Ecosystem Interaction
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … The work builds off a longstanding partnership between the JGI and Oak Ridge National Laboratory, dating back to the … and DE-AC05-76RL01830 (PNNL). … BioScales project on JGI Genomes Online Database … BioScales project on National …
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Doubling Down on Known Protein Families
… at protein function within them. The work was led by a team of scientists at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … novel genes.  They took what they were left with and clustered them into families. From there they focused on …
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CSP Functional Genomics
… function.  The emphasis is on projects leveraging JGI’s DNA synthesis and ‘omics capabilities to enhance … without the capabilities and expertise available at the JGI. Proposals to this call may be submitted to the JGI at any time using a simple web-based form and are …
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Better Genome Editing for Bioenergy
A team has optimized a crucial part of CRISPR-Cas9 technology … was a multi-institutional effort led by then-graduate student Cory Schwartz and his advisor Ian Wheeldon, a … at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User Facility. Y. lipolytica …
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Informatics Advisory Committee
The IAC is chartered by the JGI Chief Informatics Officer (CIO) and reports to the JGI Director. The IAC is chartered to render advice, … the effective management and strategic objectives for the JGI’s data science, informatics and information technology …
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A Natural Mechanism Can Turbocharge Viral Evolution
… target on the microbial cell’s membrane. Two decades ago, a team discovered a group of viruses that had in their genomes … the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user facility located at … data, approximately half of which was generated by the JGI, to uncover these DGRs. DGRs were found in single …
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … this shattering trait – referring to the moment when the cluster of seeds at the tip of each branch breaks apart so … the plant to be collected.  Association mapping led the team to identify a gene called Less Shattering 1 (SvLes1); …
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … ( The annotated algal genome is available on the JGI’s PhycoCosm data portal.) This research not only sheds … et Technologies (FRQNT) for Québec Océan and an FRQNT Team grant to C.L. The analyses were conducted using Digital …
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Extracting the Secrets of Secondary Metabolites
CRAGE-CRISPR combo helps further demystify biosynthetic gene clusters.  The Science Microbial secondary metabolites, … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … CRISPR to knock out or activate genes, researchers at the JGI were able to monitor loss- and gain-of-function. The …
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The Case for Conservation
… question. In a recent Scientific Advances article , a team led by McDaniel and his former graduate student Sarah Carey, now at the HudsonAlpha Institute for … to evolve so rapidly in gene content and structure. He and JGI Plant Program head Jeremy Schmutz already see how …
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