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A Community Resource for Secondary Metabolite Researchers
… public database for the research community. With more than 13 million BGCs in the catalog at the time of publication, … the Secondary Metabolism Collaboratory  … Browse BGCs … Natural Prodcast: Jackie Winter and SMC …
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Identifying the Microbial Cleanup Crew at a Superfund Site
… involved in a bioremediation effort. The Science In 1999, the Environmental Protection Agency declared the North … type of food that was in the contaminated aquifer in 2007 to achieve this goal. In less than four years, parts of the shallow portions of the groundwater were nearly …
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Better Genome Editing for Bioenergy
A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, but these … genes were essential to  Y. lipolytica . They identified 1,377, or 17.5 percent, of  Y. lipolytica ’s genes to be …
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Computationally Classifying Fungal Lifestyles
… an algorithm that “taught” a computer how to classify 101 representative genomes of Dothideomycetes, the largest … The machine “learned” to identify data generated in part through the 1000 Fungal Genomes Project, including 55 … (green). (From Haridas S et al.  Studies in Mycology , 2020.) Using whole genome data from newly sequenced genomes, …
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Environmental Genomics Group
Catalog of Earth’s Microbiomes .  Nature Biotechnology . 2020 Nov 9. Vyshenska, Dariia et al. (2023)  A standardized … for stable isotope probing metagenomics . mSystems , e01280-22. 10.1128/msystems.01280-22 Clum, A. et al. (2021)  DOE JGI metagenome workflow …
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Facile Recoding of Selenocysteine in Nature
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The Trichoplax genome and the nature of placozoans
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Unveiling plasmid diversity in nature
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Phage–host coevolution in natural populations
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… dead cells recorded. Samples were taken again at two, six, 12 and 24 hours. By the 24-hour mark, these algae showed … active under different conditions. This was facilitated in part by RNA library preparation and sequencing from the U.S. … in sustainable practices, such as biofuel production and natural fertilizers. By understanding the genetic and …
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User Executive Committee Charter
The JGI User Executive Committee (UEC) represents the JGI user community and is responsible for providing input and advice on JGI policies and practices that affect users and their …
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Scaling Up Existing Skill Sets
… to functional genomics. Hear from five of the Summer 2019 interns, who briefly shared their experiences below. … the requirements and responsibilities of being part of a research institute. It has also introduced me to a …
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