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JGI@25: Cow Rumen and the Early Days of Metagenomics
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … coherent pieces called contigs — into genes and even into genomes — from these environmental samples,” said Matthias … of rumen-digested switchgrass, researchers isolated and sequenced DNA from rumen microbes involved in the digestion …
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What Happens Underground Influences Global Nutrient Cycles
… DOE user facilities EMSL and JGI announce FY 2020 collaborative FICUS projects. … for User Science (FICUS) program, two Department of Energy (DOE) Office of Science national user … Molecular Sciences Laboratory (EMSL) and the  DOE Joint Genome Institute (JGI)—have selected 11 proposals for …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under … Researchers with the Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user … The team also identified previously unknown promoter sequences within these gene clusters, offering new …
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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … in Streptomyces coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions … the 5’-ends by 5’-end sequencing, from which those promoter sequences recognized by a given sigma factor are inferred. …
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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows … ago, a team discovered a group of viruses that had in their genomes a surprising tool: a “diversity generating … The work conducted by the U.S. Department of Energy Joint Genome Institute is supported by the Office of Science of …
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Nandita Nath
… Nandita is involved in developing new methods to improve genome recovery from single cells and to build sequencing libraries from minimal DNA input …
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An Inside Look at How Plants and Mycorrhizal Fungi Cooperate
… A new view into a symbiosis could offer benefits to address climate change: pulling atmospheric carbon into soil and boosting … scientist at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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Mike Sneddon
… Dr. Sneddon is the Advanced Analysis Group Lead in the Data Science and Informatics Department at the Joint Genome Institute. His team of engineers and scientists builds and operates the data and … Arkin, AP, et al. KBase: The United States Department of Energy Systems Biology Knowledgebase. Nature …
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Danielle Goudeau
… Danielle operates the single-cell genomics pipeline for JGI … combines custom flow cytometric analysis, cell sorting, genome amplification, PCR screening, and 16S sequencing. She also develops novel flow cytometry protocols for targeted recovery of specific microbes. …
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IMG/VR
… JGI's Simon Roux describes the structure and content of the IMG/VR v3 database (img.jgi.doe.gov/vr), the latest release of IMG database dedicated to viral genomes assembled from metagenomes. He also demonstrates … to browse and search through the more than 2 million viral sequences available in IMG/VR v3. …
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When “The Blob” Made It Hotter Under the Water
… impact on marine microbial communities. The Science A team of researchers tracked the impact of a large-scale heatwave … samples. Genomic DNA extracted from the water samples were sequenced by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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Rex Malmstrom
… Dr. Malmstrom is a Staff Scientist and leader of the Microscale Applications group. Before … genomics pipeline that provides JGI users access to the genomes of uncultured microbes.  His group also handles the … Ph.D. in Marine Biology/Biochemistry, University of Delaware BA in Biology, Boston University ( magna cum …
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