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… chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under … Researchers with the Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user … The team also identified previously unknown promoter sequences within these gene clusters, offering new …

… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … in Streptomyces coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions … the 5’-ends by 5’-end sequencing, from which those promoter sequences recognized by a given sigma factor are inferred. …

… The Science Anaerobic fungi, which die in the presence of oxygen, dwell in herbivore guts and help them digest … called natural products . Yet, combing through the genomes of four anaerobic fungal species has revealed, for … finnis . In work reported in 2017, the fungal genomes were sequenced by the U.S. Department of Energy (DOE) Joint …

… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing … ago, a team discovered a group of viruses that had in their genomes a surprising tool: a “diversity generating … by scientists at the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user …

… Nandita is involved in developing new methods to improve genome recovery from single cells and to build sequencing …

… A new view into a symbiosis could offer benefits to address climate change: pulling atmospheric carbon into soil and boosting biofuel feedstocks with less fertilizer. For millions of … scientist at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …

… in the Data Science and Informatics Department at the Joint Genome Institute. His team of engineers and scientists builds and operates the data and … science.  Dr. Sneddon is an accomplished leader in data, software, compute, and AI for large-scale genomics and lab …

… combines custom flow cytometric analysis, cell sorting, genome amplification, PCR screening, and 16S sequencing. She … novel flow cytometry protocols for targeted recovery of specific microbes. …

… JGI's Simon Roux describes the structure and content of the IMG/VR v3 database (img.jgi.doe.gov/vr), the latest release of IMG database dedicated to viral genomes assembled from metagenomes. He also demonstrates … to browse and search through the more than 2 million viral sequences available in IMG/VR v3. …

… Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, … production of biofuels and renewable chemicals, developing genome engineering tools for non-model organisms, modulating …

… impact on marine microbial communities. The Science A team of researchers tracked the impact of a large-scale heatwave … samples. Genomic DNA extracted from the water samples were sequenced by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …

… Click the cards below to view downloadable pdfs of previous Progress Reports from the Joint Genome Institute.  …