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JGI@25: Cow Rumen and the Early Days of Metagenomics
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … coherent pieces called contigs — into genes and even into genomes — from these environmental samples,” said Matthias … of rumen-digested switchgrass, researchers isolated and sequenced DNA from rumen microbes involved in the digestion …
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What Happens Underground Influences Global Nutrient Cycles
… for User Science (FICUS) program, two Department of Energy (DOE) Office of Science national user … Molecular Sciences Laboratory (EMSL) and the  DOE Joint Genome Institute (JGI)—have selected 11 proposals for support from 53 received through a joint … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under … Researchers with the Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user … The team also identified previously unknown promoter sequences within these gene clusters, offering new …
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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … in Streptomyces coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions … the 5’-ends by 5’-end sequencing, from which those promoter sequences recognized by a given sigma factor are inferred. …
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Gut Fungi: Unexpected Source of Novel Chemicals
… The Science Anaerobic fungi, which die in the presence of oxygen, dwell in herbivore guts and help them digest … called natural products . Yet, combing through the genomes of four anaerobic fungal species has revealed, for … finnis . In work reported in 2017, the fungal genomes were sequenced by the U.S. Department of Energy (DOE) Joint …
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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing … ago, a team discovered a group of viruses that had in their genomes a surprising tool: a “diversity generating … by scientists at the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user …
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Nandita Nath
… Nandita is involved in developing new methods to improve genome recovery from single cells and to build sequencing …
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An Inside Look at How Plants and Mycorrhizal Fungi Cooperate
… A new view into a symbiosis could offer benefits to address climate change: pulling … scientist at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … led the work in collaboration with JBEI as part of the 2021 Laboratory Directed Research and Development (LDRD) …
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Mike Sneddon
… in the Data Science and Informatics Department at the Joint Genome Institute. His team of engineers and scientists builds and operates the data and … science.  Dr. Sneddon is an accomplished leader in data, software, compute, and AI for large-scale genomics and lab …
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Danielle Goudeau
… combines custom flow cytometric analysis, cell sorting, genome amplification, PCR screening, and 16S sequencing. She also develops novel flow cytometry protocols for targeted recovery of specific microbes. …
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IMG/VR
… JGI's Simon Roux describes the structure and content of the IMG/VR v3 database (img.jgi.doe.gov/vr), the latest release of IMG database dedicated to viral genomes assembled from metagenomes. He also demonstrates … to browse and search through the more than 2 million viral sequences available in IMG/VR v3. …
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When “The Blob” Made It Hotter Under the Water
… impact on marine microbial communities. The Science A team of researchers tracked the impact of a large-scale heatwave … samples. Genomic DNA extracted from the water samples were sequenced by the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …
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