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A Sorghum Pangenome Opens More Doors to Discovery
… Leveraging decades of technological development, dozens of reference genomes and … Faculty Investigator at the HudsonAlpha Institute for Biotechnology Genome Sequencing Center and a member of the JGI … Berkeley National Laboratory, is committed to advancing genomics in support of DOE missions related to clean energy …
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An Enzyme System to Help Catalyze Bioproduction of Plastic
… of chemicals and plastics with this system. “From a biotechnology standpoint, we can make ethylene from certain … Science Program help advance DOE interests in the biotechnology innovation ecosystem. “At JGI, we’ve done the … Berkeley National Laboratory, is committed to advancing genomics in support of DOE Office of Science Biological and …
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Extracting the Secrets of Secondary Metabolites
… study in which researchers paired CRISPR and CRAGE technologies. While CRISPR (Clustered Regularly Interspaced … Recombinase-Assisted Genome Engineering) is a technique researchers can use to integrate large genetic … make up the foundation for a slew of vital products in biotechnology, medicine, agriculture, and other industries — …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… of these two pathogens, led by the JGI and Virginia Polytechnic Institute State University, was released to the … led the charge to develop rapid diagnoses for SOD. These techniques were also instrumental in tracing the genetic …
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A Community Resource for Secondary Metabolite Researchers
… metabolites are useful in a variety of fields including biotechnology, medicine and agriculture. This comprehensive …
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An Inside Look at How Plants and Mycorrhizal Fungi Cooperate
… expression in both plant cells and fungal cells. Using a technique called single nuclei RNA sequencing, the … their gene expression. Then, the researchers used a technique called spatial transcriptomics, to generate maps of gene expression. This spatial transcriptomics technique allowed them to understand gene expression within …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… National Laboratory, and the HudsonAlpha Institute for Biotechnology sequenced sphagnum  genomes from plants selected …
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An Addiction Crucial to a Fungus’ Reproduction
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… sequencing across multiple time points with Cappable-seq, a technique that precisely maps where transcription begins on … Research program’s efforts in advancing genome-based biotechnology.  Researchers studying Streptomyces species or …
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New Research Sheds Light on Diversity in the Deep Sea
… other biomolecules that could potentially be applied to biotechnology and medicine. A more robust understanding of … communities could lead to the development of new biotechnologies around clean energy,  biofuels and … at Lawrence Berkeley National Laboratory, contributed metagenomic sequencing to the study as well as  genome analysis, …
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An Automated Tool for Assessing Virus Data Quality
… data quality. The Science Through advances in sequencing technologies and computational approaches, more and more … from the host organism. As reported in Nature Biotechnology , a team from the U.S. Department of Energy (DOE) …
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How Filamentous Fungi Sense Food
… Filamentous fungi are also being used in the biotechnology industry to produce enzymes, proteins, and other … Academy of Sciences . Researchers applied multiple omics techniques to reconstruct and model the gene regulatory … ranged from simple sugars to plant biomass. One of these techniques was DAP-seq, a high-throughput method for …
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