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… just– and then in terms of there’s sequencing an organism by shotgun, which is what we did, we didn’t even sequence … mammalian systems. But it allows us to assay on a single cell level against cell lines and against primary cells isolated from patients …

… datasets, particularly for uncultivated microorganisms, by sequencing large populations of bacteria and archaea in their natural environments using single cell approaches. This includes linking strain-level genetic … catalog : Beyond minimal draft and improved draft microbial genomes the program offers single-cell sequencing, …

… synthesis, metabolomics and analysis will be paid for by the Department of Energy’s funding of the JGI. There is … merit, DOE mission relevance , proposed data usage by the applicant/community, and track record of the …

… looked like. I was imagining some massive contraption for amplifying genes. I wasn’t really sure what actinobacteria … there have been huge advances in both. The cool thing about genomes is you can, well, if your assembly is good, you can … community-built resource for experimental protocols, media recipes, plasmid maps, useful software tools, and more. We …

I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As … can just mediate so many kinds of interactions. And by understanding them, we can promote the health and … so many bacteria, because it is so easy to sequence their genomes comparatively to especially plants. So yeah, so from …

DAN UDWARY: So Alison, I’m really excited today. We have, by far, I think, one of the most decorated and legendary … that the molecules out there would be toxic to cancer cells. And that started something big. Because at that time, … So, this was when we started saying, we have to have the genomes. We have to look at the full picture of these. And …

… we don’t recognize, because the only way to find things is by comparison. We’ll talk about that when we talk about … that – I want to say like lipid bilayer, you know, in the cell.  DAN: It depends on lifestyle. So there are lots of … and you can see that different Frankia have different size genomes depending on what kinds of plants, and what kinds of …

… for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with … of the claimed genome sequences. This opportunity, provided by the Department of Energy Joint Genome Institute, builds upon thousands of microbial genomes that have been sequenced by the JGI though not …

Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … approaches to assess microbial activity across ecosystems.  By studying microbial communities and their interactions, … catalog of viral, microbial, and microeukaryote genomes and mobile genetic elements, linked to custom …

… bioenergy, environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the … culture collections to produce hundreds of diverse algal genomes, which will be made accessible through the PhycoCosm …

… a great opportunity to learn more about JGI, hear some excellent talk from our users and from other invited guests, … with my boss, JGI Director Nigel Mouncey. DAN: I’ll start by saying this is the first in-person recording that I’ve … just kind of really piqued my interest in science.  DAN: Excellent, Yeah. OK, cool. So then what specifically about …

… quantities of DNA derived from individual environmental cells. The proof of principle study built off earlier … finished genome derived from an uncultured bacterial single cell – a symbiont of the green sharpshooter. In 2012, single … identify, and characterize more than 200 microbial genomes that were mapped to nearly 30 major previously …