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So I built a lab to do that. And then yes, we had several targets– mechanistic enzymology targets and biosynthetic … goal of this research then? Is it to understand that ecology? Or are you still doing drug discovery BRIAN … we’re targeting what we think are privileged classes of molecular diversity and then plugging that into these …

… one metabolite. They produce a large array of different molecular species related– chemically related– but … that are produced, and we don’t know what potentially other targets, if there are actually other targets. So Firn and … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … provides customized analysis, the JGI also participates in publication of results. … Proposals for the annual FICUS … at Oak Ridge National Laboratory  Center for Structural Molecular Biology . … Accessing NEON’s Environmental Sample …

Research in the Woyke laboratory focuses on the utility of … … Research Interests … Former Lab Members … Selected Publications … For further details, please reach out to the …

… to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … diversity and integrating various data types to explore the molecular mechanisms behind phenotypic evolution. It also … the ability to discover syntenic orthologs, generate publication quality graphics and explore pangenome views of …

FY 2025 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours Goal Actual Total* Actual % of Goal Goal (hours)** Actual Total Actual % Goal FY 2025 … Goals and Results Fiscal Year Sequence (GB) Operating Hours Targets Actual* Targets Actual 2007 40 39.22 8400 8609 2006 …

Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI.  Additionally it includes instructions on … and storage (from PacBio) Best practices for High Molecular Weight DNA extraction and quality control (from …

… is focused on genomic science projects that address sustainable biofuel and bioproducts production, leveraging systems-based … capabilities of plants, microbes and microbial communities, global carbon and nutrient cycling, and biogeochemistry — …

… … DAN: Hey, everybody. Welcome back for another episode of Natural Prodcast. Right now I’m working on this the … communication. It’s really, really important part of their ecology, are these cells communicating with one another. … up on previous Natural Prodcast episodes  here . Show Notes Publication: Suo Z et al. A Mesorhizobium japonicum quorum …

Find protocols provided by JGI and the JGI user community below for DNA preparation tools, high molecular-weight DNA extraction and RNA preparation.  JGI … be found here . DNA Extraction Protocols: … Tips for High Molecular Weight DNA extraction: … RNA Extraction Protocols: …

… is by comparison. We’ll talk about that when we talk about molecular biology.  But um, yeah, so secondary metabolism is … know, like an organism. They have specialized cells and the ecology there is really fascinating, probably a bit under … there’s always a need to find new antibiotics that hit new targets because if you haven’t – So resistance comes about …

… my interest. And it was in another course, in a tropical ecology course, that I first encountered the term … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as … are probably quite familiar with GNPS as a tool, and using molecular network analysis, too, as an early step. That’s …