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… has a book called The Plant Hunter and I’ve read all 400 pages of her life and I feel like I have a new friend that … I also feel like Cassandra Quave has put herself on the page and made herself really knowable through her book. And … than HIV/AIDS does every year in the US and it has since 2005 even though we technically have a number of different …

… because they’re so reactive. BEN: …going back to the 1950s. But the structure of which was not known until the … among the 70,000 microbial natural products total, about 500 drugs have been out of these natural products. So this … from bacteria. And he wins the Nobel Prize in the 1950s. So this really triggers the so-called golden age of …

… from 1940 to 2000. As you can see, from the 1940s, into the 50s into the 60s, there was a huge growth – a huge explosion …

… was bioengineering bio-process R&D, BBRD, a group of about 75 people. So our biggest project was the spinosyn family of … throughput screening platform where we’d look at 10,000, 15,000, 20,000 mutants a week. We started doing a whole bunch … 30 to September 1st. The link is found all over JGI’s web pages.  DAN: And I will put it in the show notes along with …

… library within that family as possible. There’s one more category of sequences that we worked with JGI on, and those … beautiful . It’s like, imagine like a conical tube, like a 50 mil Falcon tube, that visually looks like a piece of …

… to: Project Manager Kerrie Barry, Cross-Field Category Fungal and Algal Program head Igor Grigoriev , Plant & Animal Science category Plant Program Library Construction Group Lead Jane Grimwood (at HudsonAlpha), Cross-Field category Research Scientist Natalia Ivanova, Biology & …

… out where I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. … Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in … in this kind of a vein. We sequenced in the end about 150,000 genomes, just to look for a very specific class of …

… Sanger Institute and Cambridge University University in 2005, where he studied RNA editing and cancer genetics. Dr. … Genomes from Single Bacterial Cells bioRxiv , 2024.01. 30.577819 2. Dicenzo et al. 2022. DNA Methylation in  Ensifer … in bacterial gene regulation. Nature methods 18 (12), 1499-1505 Shulse et al. 2019. Engineered Root Bacteria Release …

… metagenomes, and metatranscriptomes. It features over 15 million viral genomes and fragments, enriched with …

… available from all the facilities participating in the FY25 call, introduces the available APS resources, and contains …

… episode 3 of the Primer! — DAN: So, you know, in the in the 50s 60s 70s, most of the exploration of this is done by …