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… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of … of interest. One such effort is targeted at environmental cells that are from candidate phyla, major branches in the phylogenetic … to only three phyla. The Woyke group uses single-cell sequencing as a means to begin filling this gap. A primary …

…   Our Sequencing Technologies Group is well-integrated across JGI departments to ensure a robust offering of sequencing capabilities and products to our users. This … automation — and further advancing sequence applications, single cell genomics, DNA synthesis, and metabolomics …

… JGI has a strong interest in seeing that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … is done in a timely fashion. The publications resulting from such efforts should specify the collaborative nature of …

… for faculty to “claim” the JGI’s unpublished microbial genomes, with the expectation that faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in ongoing …

… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, DNA synthesis … the product and deliverables as well as target cycle times from sample receipt to completion of standard analysis.  Raw data is provided for all sequencing products below. In addition, JGI will submit raw …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with individual cells. Research Team    … that allow us to select specific uncultivated microbes for sequencing based on their level of metabolic activity …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore … The Microbial Program focuses on using advanced sequencing technologies to explore microbial diversity — … of bacteria and archaea in their natural environments using single cell approaches. This includes linking strain-level …

… We use multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning … discovering and characterizing giant viruses, which possess genomes and particle sizes that rival those of cellular … environmental samples. This work combines third generation sequencing and machine learning to enable fast, accurate …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … and reconstruct metabolic properties encoded within those genomes. Our aim is to more fully capture microbial and …

… beyond what each of these facilities could generate by itself.   Accepted projects must address or be otherwise … to DOE mission is appropriate. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … provides customized analysis, the JGI also participates in publication of results. …

… I got the chance to do genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … really the same kind of thing. Before the age of genome sequencing, we had to basically break up the pieces of DNA …