Search

… of natural products, Professor Bill Fenical from Scripps Institution of Oceanography in San Diego. Bill is a pioneer … an exploration into the secondary metabolism of some more novel marine bacteria. You know, I first met Bill as a postdoc working … natural products, his experiences in drug discovery, and exploring marine bacteria for novel chemistry. Related …

… recognized and credited for their work, while also adhering to the authorship policies of the journal in which the … that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … is done in a timely fashion. The publications resulting from such efforts should specify the collaborative nature of …

… is focused on the discovery and characterization of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics … Exploring the fascinating world of giant viruses, which … and complexity, and encode for a treasure trove full of novel genes ready to be tapped for downstream applications. …

… “Adopt a Genome” is an informal program for faculty to “claim” the JGI’s … faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … talent for biosciences.  Adopt-a-Genome has: ~20 faculty from institutions across the country Efforts in ongoing …

… The Metagenome Program uses advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work encompasses bacteria, archaea, and micro-eukaryoes, along with their … associated viruses and mobile genetic elements. Beyond exploring and characterizing microbial diversity, work in …

… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore the vast and diverse world of microbes. Studying bacteria and archaea, including those associated with … in particular to study inter-organismal interactions. Novel approaches are being explored to predict microbial …

… Research in the Eloe-Fadrosh group focuses on using genome-resolved … approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … And a lot of us moved on to work in simpler systems, like bacteria, where we figure we can make more progress faster, … – have related all of these different types of ribosomal pathways to each other. And so, that kind of group dynamic …

… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … ALISON: Marcy, is that something that your lab is exploring?  MARCY: Mm-hmm, so this gets back to Dan’s … We find chemistry that’s known, or sometimes novel, but often known, and yet the clusters don’t look the …

… currently exist. We looked at chemistry, so it’s really novel. And they’re just really exciting. And it really kind … far off are we from being able to, say, see biosynthetic pathways? Or can we see a progression in metabolites and … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… Biology is currently experiencing a revolution brought on by rapid developments in genomics and other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational technology … of the functional dark matter as well as the development of novel methods to enable large-scale comparative analysis, …