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… using ancestral sequence reconstruction”,  PNAS.  2023,  120, e2218248120. doi : 10.1073/pnas.2218248120 …

… of secondary metabolism. Welcome back. This will be episode 12 of Natural Prodcast. And it’s our conversation with … Europe. So if there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And I think you’ll enjoy it. So here it is, episode 12 with Nadine Ziemert. DAN UDWARY: Hey, Alison. ALISON …

… this policy) produced through all user projects accepted FY22 and later through the Community Science Program (CSP), … during the transition to the above JGI Data Policy. Pre-FY22 proposals: Proposals accepted before FY22 are transitioning away from producing use-restricted …

Department of Energy operated under Contract No. DE-AC02-05CH11231.” … All publications using JGI data produced under a … products produced through all user projects accepted FY22 and later. … Read about our policy on research data and …

… as well as a unique opportunity to complete a California K-12 science or math teaching credential as an undergraduate …

… the minimum is 100 kb, and for metabolomics, at least 22 samples are required. If your proposed request falls …

… there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re trying to do … happening. And so we should have somewhere around 10, 11, 12 million BGCs in the database on the release, and that’s …

… right? BEN: Yeah, yeah. Well, we are at [10 to the] minus 12 [Molar concentration]- is sufficient to kill cells. So … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain …

… in Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in … this is Challis et al, Chemistry and Biology, 2000, 211-224, 7:3 And so, you can then make predictions about NRPS’s … Microbiomes” paper is here . Read the associated JGI news release here . Software we discussed, used for genome …

… and against primary cells isolated from patients up to 12 markers at a time. And these are phenotypic markers. So … Nikolaou synthesized the everninomicin at Scripps, I guess, 22 years ago. And it’s over 130 steps to make everninomicin. …

… within the realm of education. … Through the Berkeley Lab K-12 program, the JGI collaborates with Biotech Partners to …

Adopt-a-Genome has:  11 CSU educators working with the JGI 120 genomes claimed (or about one per student) Seven … entomopathogenic nematodes: Xenorhabdus cabanillasii DSM17905, Xenorhabdus ehlersii DSM16337, Xenorhabdus japonica DSM16522 R Robertson, et. al.  2023 . Microbiology Resource …