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… of the functional dark matter as well as the development of novel methods to enable large-scale comparative analysis, … Genes. Cell 178(5):1245-1259 Nayfach S, et al, (2019) New insights from uncultivated genomes of the global human gut … Science 344(6186):909-13 … Research Efforts … Selected Publications … For further details, please reach out to the …

… that the data produced by the facility result in scientific publications. JGI users and collaborators have the right to … (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any … is done in a timely fashion. The publications resulting from such efforts should specify the collaborative nature of …

… that govern ecosystem processes. This research provides insights into microbial diversity and metabolic potential, … regulation, and noncoding RNAs in microbiomes. The insights from this work have the potential to drive innovations in … most pressing challenges. … Exploration of phylogenomic novelty: Advances in metagenomic sequencing, assembly and …

… faculty will work with undergraduates in the analysis and publication of the claimed genome sequences. This … … A primary purpose of this project is to bring educators from a broad range of disciplines up-to-speed with some of … and skills necessary to extract meaningful biological insights from sequence data, employing IMG data and tools …

… such effort is targeted at environmental cells that are from candidate phyla, major branches in the phylogenetic … means to begin filling this gap. A primary goal is to get  insights into the coding potential of candidate phyla  to … … Research Interests … Former Lab Members … Selected Publications … For further details, please reach out to the …

… genomics with metabolomics fuels the discovery  of novel metabolites, genes, and proteins. It also enables … microbes, and understanding microbiome interactions. The  insights derived are crucial for advancing the bioeconomy, … mass spectrometry-based methods to analyze metabolites from a wide range of biological and environmental samples — …

… genome mining on more than 50,000 genomes that we derived from meta-genome sequences. As always, you’ll find … and how we do it here and maybe give an example of a recent publication. ALISON TAKEMURA: Awesome. Yeah, let’s dive in, … machine learning really would help distinguish and predict novel gene clusters. DAN UDWARY: Yeah, it certainly could. …

… cycling and inter-organismal interactions. These insights are crucial for addressing key environmental … in particular to study inter-organismal interactions. Novel approaches are being explored to predict microbial … of sequence space:  The JGI generates reference genomes from diverse bacterial and archaeal lineages to improve …

… group aims at improving our collective understanding of ecological and evolutionary parameters driving virus:host … involves both experimental and computational exploration of uncultivated viral diversity, characterization of molecular … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct metabolic … Microbiology , 15032. 10.1038/nmicrobiol.2015.32 … Selected Publications … For further details, please reach out to the …

JGI Mission As a U.S. Department of Energy Office of Science user facility supported by the … large-scale data and professional expertise to support the global research community in studies of complex biological …     Our homepage video includes external footage from:  University of Delaware Laura.Selbmann©PNRA. All the …