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… of secondary metabolism. Welcome back. This will be episode 12 of Natural Prodcast. And it’s our conversation with … Europe. So if there are any kind of dated references to the news, that’s why. But it was a really fun conversation. And … this? NADINE ZIEMERT: It wasn’t that long ago, but maybe 2006, 2007, or something like that. And we actually found the …

… 10 to the negative 9th. Picomolar, 10 to the negative 12th. DAN: Yeah. So very-- BETSY PARKINSON: Very, very-- … thioesterases, we were actually able to find approximately 300 with NRPSs nearby. And of those once we did the … the issues is in order to make the tetrapeptide, that's a 12 membered ring. And there's extreme ring strain in 12 …

Photon Source when applying to the FICUS call. (Feb. 21, 2024) More JGI webinars below …

… as well as a unique opportunity to complete a California K-12 science or math teaching credential as an undergraduate …

Great Salt Lake, which is a hypersaline terminal lake about 30 minutes away from campus. And we’re finding some really, … there a way to do that? DAN UDWARY: Well, so there’s good news and bad news on that. So one of the things that we’re … happening. And so we should have somewhere around 10, 11, 12 million BGCs in the database on the release, and that’s …

… right? BEN: Yeah, yeah. Well, we are at [10 to the] minus 12 [Molar concentration]- is sufficient to kill cells. So … So I wanted to ask you also about – because you were in the news recently – TSRI has acquired the Pfizer strain … genome, the genome predicts they often can produce around 30 – more than 30 compounds. So, this was a complete …

… within the realm of education. … Through the Berkeley Lab K-12 program, the JGI collaborates with Biotech Partners to …

… in Yu et al, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 1253–1262, 70:3 ALISON TAKEMURA: And so did you succeed in … this is Challis et al, Chemistry and Biology, 2000, 211-224, 7:3 And so, you can then make predictions about … Microbiomes” paper is here . Read the associated JGI news release here . Software we discussed, used for genome …

Adopt-a-Genome has:  11 CSU educators working with the JGI 120 genomes claimed (or about one per student) Seven … available datasets encompassing >150,000 isolate genomes, 230,000 metagenome-assembled genomes (MAGs), and 40,000+ … et. al.  2023 . Microbiology Resource Announcements. 2023 12 (10), e00548-23 Whole genome sequence of the denitrifying …

… proposal submission. Sequence requests should not exceed 3 Tb in total. Proposals for this call may be submitted at …

… metagenomics. Nature Reviews Microbiology volume 20, 721–736 JC Villada, F Schulz (2022) The endosymbiotic box of … through global metagenomics. Nature. 578 (7795), 432-436 Schulz et al. (2020) Advantages and limits of …

… like a nice summer day in Seattle I think this was like 2013 or 2014. And antiSMASH — I know you’ve interviewed Marnix … access to the whole sigma catalog of precursors in their 12C form. You can feed those and look for incorporation in … by Inverse Stable Isotopic Labeling . ACS Chem Biol. 2021 Aug 20;16(8):1332-1338. doi: 10.1021/acschembio.1c00329. …