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JGI@25: Building a Better Bean
… In honor of the JGI's 25th anniversary in 2022, we have … number of notable achievements that showcase our collaborations and capabilities to enable great science that will help solve energy and environmental challenges. While a hill of beans may not seem to …
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JGI@25: From Life at the Extremes to Editing Genomes
… In honor of the JGI's 25th anniversary in 2022, we have … system’s immense collection of publicly accessible metagenomic datasets from a wide variety of ecosystems around … nature was using it to do something important.” Related Publications:  A scoutRNA Is Required for Some Type V …
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Gene Expression: From On-Off Switch to Dial
… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science … a more nuanced library approach to tuning gene expression in metabolic pathways. Compared to the traditional way, which leverages an all-or-nothing approach to … No. FA9550-14-1-0089, the Camille and Henry Dreyfus Foundation, and the JGI Synthesis Program under FP00005685. In …
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Exploring Possibilities: 2022 JGI-UC Merced Interns
… Edward Lu and mentor Miguel Romero Sean Saki and mentors  Zhong Wang and Bryce Foster Sivagunalan Thamilarasan and mentors Zhong Wang and Bryce Foster Feng Yu and mentors Zhong Wang and Bryce Foster Irina Birskis Barros and mentors …
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Kjiersten Fagnan
… with JGI in 2012 as a NERSC bioinformatics computing consultant, after completing a petascale postdoctoral fellowship at NERSC and LBNL’s Computational Research Division. As a postdoc, her research focused on stable and … Informatics Officer provides advice and strategic direction for the overall design and implementation of …
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Pinning Down a Piece of Photosynthesis
… By studying the structure and function of a cyanobacterial protein, researchers have new … insights into how these ocean photosynthesizers cycle carbon in changing conditions. The products of photosynthesis … longtime JGI collaborator Sabeeha Merchant’s group. In 2011, they inventoried a swath of blueprints to find parts …
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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing environments. The Science The first step in the deadly dance … sampled all at once from the same environment, called metagenomes. Why? Simon Roux, who led the research team and is …
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Better Genome Editing for Bioenergy
… technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput … help scientists engineer organisms for bioenergy applications. Cas9 needs guide RNA to lead it to the correct sequence … yeast. The Impact The team used this set of guide RNAs on  Yarrowia lipolytica to identify essential genes and …
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JGI Announces FY26 Large Scale Portfolio for Our Community Science Program
… Coleman and Hugh Cross; [Below] Zac Freedman, Martin Jonikas, Lotus Lofgren, Fumito Maruyama, Lauren Stadler, … Scale call. This portfolio accelerates bioenergy innovation through genomic discovery across diverse organisms and … Microbiome Data Collaborative (NMDC) to produce open metagenomics data. Taking the JGI’s call for large-scale …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… deep subsurface ecosystem. The Science Altiarchaea are carbon-fixing microbes and targets of multiple viruses in … resist. The battle waged below the Earth’s surface is reconstructed by combining a study of microbial communities (metagenomics) and a chemical labelling approach. The Impact …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… Bacterial enzymes play second fiddle to those from fungi when it comes to breaking … of researchers have found that there is a striking division of labor between the two groups. Fungi are much more … to identify proteins, the team compiled DNA sequences (metagenomes) and messenger RNA sequences (transcriptomes) from …
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Waiting to Respire
… to ancestral bacteria’s energy sources. More than two billion years ago, cyanobacteria acquired the ability to produce … as a byproduct. The abundance of oxygen shaped the evolution of life on Earth, and led to the development of … Paula Matheus Carnevali was working with a group of metagenome-assembled genomes (MAGs) dubbed Margulisbacteria, …
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