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Secondary Metabolites Program
… growth, provide critical advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and communication. … to tap into the largely unexplored biochemical diversity within secondary metabolites, expanding their potential … experimental approaches to explore the synthesis and function of these biologically significant compounds. By …
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The Experiment Data Depot: A Web-Based Software Tool for Biological Experimental Data Storage, Sharing, and Visualization
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Contrasting Community Assembly Forces Drive Microbial Structural and Potential Functional Responses to Precipitation in an Incipient Soil System
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JGI-UC Merced Interns Share Their 2021 Experiences
… During the summer of 2021, 13 interns from UC Merced spent eight weeks working virtually with JGI mentors to investigate rigorous research projects, … Blurring the Line Between Plasmids and Phages … Evolution of the Mitochondria Internship … Cross Species Integration of Single Cell Transcriptomes …
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An Enzyme System to Help Catalyze Bioproduction of Plastic
… By characterizing the structure and function of a methylthio-alkane … Leveraging resources from user facilities funded by the Biological and Environmental Research (BER) program, … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User …
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Unlocking the potential of metagenomics through replicated experimental design
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… These analyses provide granular insight into microbial functions, traits and competition, illuminating the inner … to really see the utility of them broaden,” Wilhelm said.  Sharing Ideas to Improve Experiments In a separate effort, … “ This workshop was really nice because people were given structure, but it was all about sharing ideas. All breakout …
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Natural Prodcast Episode 2: The Primer, Part 2
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … 2 of our “primer” episode, so if you ended up here somehow without having listened to the first part, you might be a … from polyketides. At least I mean, I haven’t looked at the structures and details for a long time. But… DAN: Yeah, …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… Trained on environmental data, a new JGI tool more accurately … biological sequences such as biosynthetic gene cluster structures. Zhong Wang, a computational biologist at … new discoveries in microbial genome structures and functions. Wang worked with the MetaHipMer team with …
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Soil virus offers insight into maintaining microorganisms
… Using the IMG/M data portal, researchers have identified a … drift and diversification processes. The high-resolution structure of chitosanase was obtained at SLAC by irradiating … why these AMGs exist in the first place, and what function other AMGs may serve.  The work was enabled in part …
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Prepublication data sharing
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Controlling selectivity of modular microbial biosynthesis of butyryl-CoA-derived designer esters
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