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… genome data, unlocking new potential for AI-driven studies of energy metabolism. The Science Researchers produced … search environmental data, they developed a two-stage metagenomic detection pipeline: First, they scanned over 26,000 … The next step applied metagenomic binning (grouping sequencing reads by their likely organism of origin) …

… Tracking evolution of symbiotic lifestyles across multiple fungal lineages. The … (form symbiotic relationships outside of the root cells) lineages. To learn why, researchers analyzed 135 … will assist researchers in moving toward functional genomics studies to learn more about the inner workings of …

… A “bait and hook” single-cell genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is a … pools, followed by whole genome amplification and shotgun sequencing. The team first tested the approach on bacterial …

… Sequence-based studies — from metagenomics to single-cell work — have quickly accelerated understanding of giant viruses. The Science In the last thirty years, in … to provide a perspective on giant virus diversity, and how sequencing and bioinformatics have sped up the study of …

… PCE (perchloroethylene) found its way into the groundwater of several communities in New Mexico via leakage from a … down PCE into the chemical compound ethene. Applying genome sequencing and analysis, the researchers identified other … Program , they were able to analyze the resulting metagenomic data. (Data from the project are available on the  …

… Analysis of haloarchaeal metagenomes broadens understanding of … haloarchaea from different Antarctic lakes. To assess the genomic variation in haloarchaea, they also characterized … hypersaline Antarctic lakes. The Impact By collecting and sequencing dominant haloarchaeal sequences from six …

… influence in their chosen field or fields through the publication of multiple highly cited papers during the last … as other year-end science discovery lists.  Updates to the Genomic Encyclopedia of Bacteria and Archaea : Under the umbrella of the GEBA, the JGI is sequencing thousands of bacterial and archaeal genomes from …

… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … knowledge. In a study published November 11, 2022, in Cell Genomics , the team focused on Actinobacteria ( … resource, but also yielding and supporting many high-impact publications ,” emphasized Markus Göker, who managed the …

… The Impact The Antarctic lakes are a “treasure trove” of unknown microbes that play critical roles in … biosphere), including the global carbon cycle. The JGI is sequencing large numbers of microbes and microbial … to carbon cycling, and is interested in understanding the genomic basis and ecological consequences of microbe-microbe …

… ice in the Arctic has decreased by more than 30% in terms of quantity and thickness. Replacing older, thicker ice with … significant stress with a higher proportion of dead cells recorded. Samples were taken again at two, six, 12 and … This was facilitated in part by RNA library preparation and sequencing from the U.S. Department of Energy (DOE) Joint …