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Taking Stock of the Known and Unknown Microbial Space
… Metagenomic datasets could help map out microbial diversity … hotspots Over the past few decades, advancements in sequencing technologies have led to an abundance of microbial genomes becoming available to the global … Berkeley National Laboratory, is committed to advancing genomics in support of DOE Office of Science Biological and …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… a new methodology, scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … usually employ two different methods; shotgun metagenomic sequencing and single-cell sequencing. For years, extracting …
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Natural Prodcast
… about natural products and the science and scientists of secondary metabolism. Natural products, secondary … research, “Natural Prodcast” serves as an important line of communication to the scientific community. Host Dan … and future developments, and how the JGI can be part of that space.   …
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A Sorghum Pangenome Opens More Doors to Discovery
… Leveraging decades of technological development, dozens of reference genomes … at the HudsonAlpha Institute for Biotechnology Genome Sequencing Center and a member of the JGI Plant Program. … Development (USAID) also supported the work.   Publication:  Morris, G.P., Harder, A.M., Healey, A.L.  et …
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2024 Progress Report
… The Integrative Genomics Building (IGB) seen above is home to the DOE Joint … Area are also co-located in the IGB. Vision  Lead genomic innovation for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide …
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First Monoploid Reference Sequence of Sugarcane
… . The Science Most species are diploids and have two sets of chromosomes, one from each parent. In contrast, many … sequence and assemble, in turn limiting the use of modern, genomic breeding in these crops. For diploid species, sequencing programs generally focus on a genotype with two …
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Sequencing the Genomes of the First Terrestrial Fungal Lineages: What Have We Learned?
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… conditions. While scientists around the world were busy sequencing the human genome, an arms race was being waged. … user facility. The staff and resources shifted to offering genomic science capabilities for energy and environmental … with the HudsonAlpha Institute for Biotechnology.   Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …
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Leo Baumgart
… his doctoral research in synthetic biology and microfluidics at the University of California, San Diego. As the Sequencing Technology Implementation Lead, he directs a … team responsible for piloting and operationalizing new genomic technologies, integrating automated liquid handling …
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From Intern to Published Scientist: The Journey of a JGI-UC Merced Intern
… For many scientists, the culmination of their work into a written report that is published in a … current PhD student, reached this milestone with a recent publication in Molecular Biology and Evolution . “It’s my … to learning about how to navigate and analyze large genomic datasets during the internship, Wint also began …
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From Sample Shipments to Sequences – A Tour of the JGI’s Sequencing Pipeline
… viruses — to support scientists around the world. Most of those researchers send their samples in from afar, without ever hearing much about the sequencing lab. So today, Chris Daum walks through the JGI’s sequencing pipeline, where there are freezers with names — …
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Olpidium, The Key to the Origin of Terrestrial Fungi
… JGI’s 1000 Fungal Genomes Project, which aims to provide genomic information for every family of fungi. In the … attracted the attention of many mycologists with the two publications of the kingdom-wide, multi-gene phylogeny of … the zoospores were then sent to the JGI for whole genome sequencing using the Illumina platform. Unfortunately, both …
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