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Better Genome Editing for Bioenergy
… technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput gene-editing tool that can help scientists engineer organisms for … not all guides are effective. To ensure the gene editing tool will make the right cut, researchers created a set of …
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JGI@25: Roots of a Mutualist Relationship
In honor of the JGI's 25th anniversary in 2022, we have … number of notable achievements that showcase our collaborations and capabilities to enable great science that will help … Institute for Agriculture, Food and Environment (INRAE). Today, there are nearly 200 mycorrhizal fungal genomes …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… enabled by the JGI DNA Synthesis Science Program. Fashioning DNA outside a cell is key to interrogating what genes … developed thousands of DNA constructs encoding a molecular tool to repress targeted genes in the organism. The team demonstrated that this tool, called CRISPR inhibition or CRISPRi, works (see the …
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SPRUCE-ing Up Science
A former JGI intern is now applying his internship lessons on presentations to peatlands Travis Lawrence sits in … JGI mentor, Zhong Wang. Together, they worked to develop a tool that leveraged machine learning to help users determine … maintains this expectation of his UC Merced interns today. Additionally,  the entire cohort is required to …
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Strain Engineering
… yeasts and algae previously with little to no genetic tools enabling heterologous expression and functional exploration.  The developed strains represent an …
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Accelerating Metagenomics Discoveries with Deep Learning
On July 6, scientists from Lawrence Berkeley National … is JGI software developer Brian Bushnell, no alignment-free tool exists for proteins. (And while Mash and BBsketch can … Resources Division (CRD), in order to create more useful tools for the bioinformatics community. Other work presented …
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Science Programs
… edge approaches for and with users, and create computational tools and resources for them. Their concerted efforts help maximize the JGI’s impact in advancing …
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Applying Viral Genomics Expertise to Understanding the Human Virome
JGI researchers lend expertise to develop tools and data hub for NIH program. While the microbes in, on and around Earth outnumber the stars in the Milky Way, … managing public viral genomics resources such as analytical tools and data repositories to two projects funded through …
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New Vision, New Mission, New Plan: The JGI’s Next Five Years
… strategic plan outlines how the JGI will advance the bioeconomy, leveraging partnerships to advance foundational … expect to offer our user community an exciting range of new tools and capabilities to support their scientific … Standardizing and streamlining the JGI’s data systems and tools, as well as interweaving those efforts into a wider …
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Partners
… science and serve as impact multipliers . The JGI has a long-term partnership with the HudsonAlpha Institute for Biotechnology for our Plant Program, … (NMDC)—to provide access to datasets, workflows, and tools to seamlessly expand data functionality. Close …
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FICUS-NERSC/KBASE
The mission of the Joint Genome Institute is to serve the scientific community as a user facility pioneering functional genomics to solve the most relevant … Knowledgebase ( KBase ) integrates systems biology data and tools to help predict biological function.   To jointly …
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Finding the Fermenters
… prokaryotes. The Science Most organisms use oxygen to convert food into energy. However, in environments with … from the  Hungate1000 project . They also used the tool to predict possible functions from 733 … metagenome-assembled rumen genomes. Finally, they used the tool to predict the fermentative end products of five …
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