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Bacteria and Fungi Divvy Up the Work in Forest Floor
Bacterial enzymes play second fiddle to those from fungi when it comes to breaking down … The Science Walk in a temperate forest filled with Norway spruce trees, and microbial activity teems beneath your … So, to be able to identify proteins, the team compiled DNA sequences (metagenomes) and messenger RNA sequences …
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Expanding Virophage Diversity
… small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages … in common: major and minor capsid proteins (MCP and mCP, respectively), ATPase involved in DNA packaging, and PRO, a … increased the number of known high quality virophage genome sequences 10-fold through computational approaches. By …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… the naked eye, microscopy reveals unexpected complexity At first glance, the slightly murky waters in the tube look … within the cytoplasm of their cells. This newly discovered species of bacteria keeps its DNA more organized. “The big … the bacterial cells on the molecular level. They amplified, sequenced and assembled the genomes. In parallel, Gros’ lab …
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2025 NeLLi Symposium
Hosted by the DOE Joint Genome Institute, the University of Nevada, Las Vegas, and the Desert Research Institute, the … metabolic and functional capabilities. Take part in the "Sequences to Cultures" Jamboree!  Immediately following the … Bacteria and Archaea revealed by a recent genome census . Speakers John M. Archibald (Keynote) Dalhousie University  …
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Triggering Morel Fruiting
A collaborative team led by Hao Tan from the Sichuan Academy of Agricultural Sciences in China … CO2 emissions from decaying leaves and woods into the atmosphere, while increasing the organic matter and fertility of … M. importuna CCBAS932 from the forests of France, were sequenced and annotated by a collaborative team. The genome …
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2024 Progress Report
… home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems Biology Knowledgebase (KBase), the … systems. We optimize our service to the community through responsibly managing our people and resources.     Director's … 39,870 projects in FY24 We generated 871 Terabases of sequence We synthesized 9.7 Megabases of DNA We processed …
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Ancient Algae Reveal Secrets of Plant Evolution
Research uncovers the genetic foundations that helped plants conquer land over 600 million … Berkeley National Laboratory (Berkeley Lab), scientists sequenced the genomes of four  Zygnematophyceae algae, which … Researchers identified key genes associated with stress responses and compared them with those found in modern plants. …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… applying a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo … domesticate some 60 strains, inserting into them a genetic sequence that acts as a “landing pad.” Mouncey adds, “Once … Pseudomonas  and Ralstonia with enzymes that make phosphate bioavailable for plants. When these engineered …
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Applying Viral Genomics Expertise to Understanding the Human Virome
JGI researchers lend expertise to develop tools and data hub for NIH program. While the microbes in, on and around Earth … potential ," is among the five focused on tool development. Specifically, the goal of this work is to develop tools, … collection of UViGs by identifying contiguous viral sequences (“contigs”) from thousands of ecologically diverse …
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Making a Lichen Together
For the first time, a team analyzes the transcriptomes of a … fixed carbon to the mycobiont. However, despite a century-and-a-half of lichen research, many of the … nitrocellulose filters in Petri dishes. The scientists also sequenced the fungus and photobiont’s genomes and compared …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of … for understanding the microbiome of the earth, but most species do not grow easily in the lab. To access the genomes … Amplification to generate enough DNA to put on a sequencer. As previously mentioned, it’s a method that’s …
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Researching and Solving Real-World Problems with the 2023 JGI-UC Merced Interns
For the first time in several years, the DOE Joint Genome … (below) to hear more about the summer from their own perspectives. The interns from this cohort and their JGI … mentor Bryce Foster, Benchmarking Bioinformatics Tools for Sequence Similarity Searching Morgan Lavenstein Bendall and …
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