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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and adaptation.    Understanding how genes are regulated is like deciphering the complex wiring … “A lot of these technologies were designed for samples from humans or mice,” said Sharon Greenblum, a co-first author on …
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Mike Sneddon
… Department at the Joint Genome Institute. His team of engineers and scientists builds and operates the data and compute platforms and bioinformatics annotation pipelines that support JGI’s portals, tools, and … where he led the Production Informatics team in delivering validated bioinformatics pipelines and a laboratory …
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A framework for human microbiome research
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The first complete human genome
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Diverse events have transferred genes for edible seaweed digestion from marine to human gut bacteria
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Data Ecosystem
… The JGI is leveraging its current partnerships to offer new capabilities and resources to users through a BER … is discoverable and accessible. Linking the resources of powerful institutions like the JGI, KBase, NCBI, NMDC, … ensure platforms are future-ready for advancements enabled by artificial intelligence and other tools. By bringing …
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Secrets of the Needles: What Microbes do on Conifer Leaves
… Novel study looks at microbiomes in aerial surfaces of plants and their roles in plant health and environmental … species and sites, reflecting ecological patterns shaped by both local conditions and the movement of microbes … The team learned that some bacterial families carry genes for degrading monoterpenes such as α-pinene, as well …
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Frequently Asked Questions: Proposal Submission
… See below for a list of Frequently Asked Questions about our proposal submission process. You can review successful letters of intent and submissions at the bottom of the page.  … Review the list of open calls ; click on the call link to see specific … supported, sample/capacity limits, and instructions.  Many of the submissions are done using web-based forms.   To view …
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A Collaboration to Improve Plant Genome Annotations Across Species
… which specializes in genome improvement for plants. As part of that partnership, the JGI and HudsonAlpha researchers led … the complete set of RNA molecules transcribed from all the genes within a cell or tissue at a specific time or under … plant species. It was developed to improve plant genome annotations at the US Department of Energy (DOE) Joint …
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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant under … more efficient microbial factories. Identifying specific genes, regulatory elements and metabolic pathways that … and high-value bioproducts. This study offers a template — integrative analysis of multiple omics data from various …
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Functional autonomy of distant-acting human enhancers
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Beyond the census of human gut dwellers
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