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… complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful … attempt to put them back into the original genomes. These metagenome-assembled genomes (MAGs) that came from shotgun … together, they found most bacterial genomes from water and soil communities were at least 80% complete when studied …

… tools and data hub for NIH program. While the microbes in, on and around Earth outnumber the stars in the Milky … categories: Catalog the human virome; Develop tools to study the human virome; Explore how the human virome … CheckV , which assesses the quality and completeness of metagenome-assembled viral genomes ( Nature Biotechnology , …

… Dr. Grigoriev joined the JGI in 2003, following his postdoctoral training at UC Berkeley … Genome Project and led annotation and analysis of diverse eukaryotic genomes, from protists to plants. In 2009, he … to learn more about the program's areas of focus, major initiatives and more.  …

… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science … optimization. Summary Life is all about balance. This study,  recently published in the  Proceedings of the … Foundation, and the JGI Synthesis Program under FP00005685. In addition, M.D. acknowledges funding from a National …

… s ditched their flagella and other traits when migrating back to the ocean. The Science Scientists have … unique array of chemicals not typically found in oceans or soils.  A recent study published in  The ISME Journal     focused on a class … ) conducted by the U.S. Department of Energy Joint Genome Institute (https://ror.org/04xm1d337), a DOE …

… RIViT-seq technology could speed up associating transcription factors with their target genes. The … that control transcription. Summary Transcription in eukaryotes is handled by three distinct RNA polymerases; in … given sigma factor are inferred. Prior to this most recent study, only 12 sigma factors and 200 genes (or 209 sigma …

… Sequence-based studies — from metagenomics to single-cell work — have quickly accelerated understanding of … and how sequencing and bioinformatics have sped up the study of giant viruses. The Impact In their existence as … reference genome, to sift for snippets of giant viruses in metagenomes. This has been useful in marine environments, …

… Team develops a computational pipeline to sift and characterize RNA virus sequences.  A zoo … one of the project co-leads and first author of the study. Members of the Tel Aviv and NCBI teams, who were … most of the known RNA viruses have been associated with eukaryotes. Along with the expansion of bacteria-associated …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements … to their economies. It also plays an important role in soil health through nitrogen-fixation and holds clues for …

… Dr. Sneddon is the Advanced Analysis Group Lead in the Data Science and Informatics Department at the Joint Genome Institute. His team of engineers and scientists … , PCT application PCT/US2021/018050 (published 2021). Arkin, AP, et al. KBase: The United States Department of Energy …

… enabled by the JGI DNA Synthesis Science Program. Fashioning DNA outside a cell is key to interrogating what genes … in the Synthetic Biology special issue, Modular cell-free expression plasmids to accelerate biological design in cells , … and her own as an early career researcher. “We were able to study hydrocarbon biosynthesis at a scale that would …

… Researchers looked across many organisms to see that aminotransferase enzymes have evolved mix-and-match … Facility located at Berkeley Lab. In addition to providing metagenome mining for computational analysis of the AT … around, regardless of malfunction or misplacement.  In studying this family of ATs, researchers found that these …