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… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements … environmental challenges.   The Human Genome Project began in 1990 when the U.S. Department of Energy (DOE) partnered …

… Microbial cells infected by viruses undergo metabolic reprogramming. The Science If it looks like a duck and quacks like a … For this project, RNA sequencing was done by the JGI, and proteomics and metabolomics analysis and microscopy at EMSL. … portion of this research was performed under the Facilities Integrating Collaborations for User Science (FICUS) …

… With a new methodology, scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for … U.S. Department of Energy Joint Genome Institute (https:// ror.org/04xm1d337), a DOE …

… and have two sets of chromosomes, one from each parent. In contrast, many crops have multiple sets of chromosomes … genomes are more difficult to sequence and assemble, in turn limiting the use of modern, genomic breeding in … The final sugarcane sequence generated is 382 Mb; 25,316 protein-coding gene models were predicted with more than 80 …

… with C. richardii The Science Fern genomes are huge, and incredibly complex — making it difficult to grasp a deeper understanding of … of ferns alive today. Boasting adaptations in order to protect themselves from environmental stresses, ferns’ … The work conducted by the US Department of Energy Joint Genome Institute is supported by the Office of Science …

… Streamlined genome with precise gene targeting transforms … organism's ability to switch between autotrophic and heterotrophic growth enables production strategies that optimize … RNA genes with unusual structures that could be useful for protein production and other biotech applications. Engineers …

… cultures reveal they are symbionts and not free-living organisms. The Science Researchers employed multiple … in 2011, Nanohaloarchaea are part of the DPANN (Diapherotrites, Parvarchaeota, Aenigmarchaeota, Nanoarchaeota, and … features of the Nanohaloarchaeota was discovered with proteomic analyses. The species harbors genes encoding SPEARE …

… Miscanthus  sequence offers insights into benefits of polyploidy and perenniality. The Science A … and genomic toolkit for the perennial grass Miscanthus sinensis has been published. Analysis of the genome sequence … This work was supported by the Energy Biosciences Institute and the DOE Center for Advanced Bioenergy and …

… The Science Eelgrass, one of the most abundant plants in the ocean, originated in Japan before spreading around the globe. Now, … in various locations.  One group investigated changes in protein sequences, while others analyzed single point … This study was supported by a PhD scholarship from the China Scholarship Council to L.Y. (number 201704910807), by a …

… forms of MGEs are viruses and plasmids. They can be found in virtually all of Earth’s ecosystems. A software tool  recently described in  Nature Biotechnology  called geNomad identifies and … Lead Nikos Kyrpides at the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …

… The Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems … who made use of our data. We completed 39,870 projects in FY24 We generated 871 Terabases of sequence We … advanced genomic capabilities. This year we brought online the latest short-read technology, the Illumina NovaSeq X …

… Understanding how a fundamental mechanism of evolution allows microbes … a virus with a “head-tail” morphology, this means using proteins on its tail fibers to latch onto a specific target … or DGR. The DGR could mutate the virus’ tail fiber proteins, and thereby allow them to embrace different cells. …