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Biodesign
…   The Joint Genome Institute's Biodesign Platform capabilities … into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, … JGI Biodesign platform enables users to validate hypotheses generated from mining genomic data by designing and …
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Tracking the Origins of Methane-Producing Microbes
… Mini-Metagenomics Approach Helps Identify Novel Archaeal … methanogenic archaea use one of three pathways for methanogenesis: hydrogen-dependent and CO2-reducing, or … and, acetoclastic. All three pathways require the gene cluster for methane production known as Mcr. Until …
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First Monoploid Reference Sequence of Sugarcane
… and have two sets of chromosomes, one from each parent. In contrast, many crops have multiple sets of chromosomes … in these crops. For diploid species, sequencing programs generally focus on a genotype with two identical sets of … sequence using a targeted approach that focused on the gene rich part of the genome by harnessing information from …
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2021 JGI Proposal Call Brings New Investigators into Community Science Program
… Accepted proposals emphasize JGI interests in algae and secondary metabolites. A total of 27 … and then use computational tools to analyze biosynthetic gene clusters and then develop them for a range of … and algae’s roles in nutrient cycling, now a facet of the  Fungal & Algal Program . For example, green algae represent …
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New and Improved: Eucalyptus Reference is Now Accessible
… An improved genome assembly to support targeted tree breeding for the bioeconomy.   The Science Researchers report a … genome for eucalyptus in the July edition of the journal G3 Genes | Genomes | Genetics , with significant advances compared to the 2014 … Borevitz) conducted by the US Department of Energy Joint Genome Institute ( https://ror.org/04xm1d337 ), a DOE …
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JGI@25: Mapping Switchgrass Traits with Common Gardens
… In honor of the JGI's 25th anniversary in 2022, we have … 2007, the JGI has been working on identifying switchgrass genes related to biomass production, drought tolerance, and … about a multi-year study his student conducted involving fungal rust pathogen resistance. Just as the common gardens …
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Fishing for Novel Cellulose Degraders
… A “bait and hook” single-cell genomic approach to bioprospecting. The Science One of the most vital pieces of equipment … DNA synthesis and cloning, followed by protein in vitro expression and mass spectrometry-based enzyme activity … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, …
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… the JGI’s 25th anniversary celebration, the 2022 Annual Meeting featured speakers who shared a look back at the JGI’s … on, from the myriad of omics analyses for understanding gene expression in plants and the environment, to the JGI’s …
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A Sorghum Pangenome Opens More Doors to Discovery
… Leveraging decades of technological development, dozens of … sequence for a line of sorghum, reference genomes have generated insight into drought tolerance, biomass production … for this plant. In other lines around the world, much more genetic diversity exists.  Now, researchers have brought …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… Trained on environmental data, a new JGI tool more accurately … discoveries. Unlocking the intricate details of life’s genetic blueprint has long been a significant challenge in genomics. Enter GenomeOcean, a powerful generative model  now available to the global research …
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Defining a Pan-Genome for Antarctic Archaea
… Analysis of haloarchaeal metagenomes broadens understanding of Antarctic biogeography. The Science Haloarchaea … shed light on the global biogeography in the haloarchaeal gene pool, a team led by University of New South Wales … Rauer Islands. Additionally, they compared metagenome data generated from samples collected at four Rauer lakes to …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… Innovative technology from this biomanufacturing … to recover high value products from human waste. They   genetically modified yeast to efficiently convert elements … and it could be sold in the United States for $50-200, generating a potential profit of $1.4 million annually.  The …
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