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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… hitchhikers. These organisms are abundant and yet exceptionally small, with mini genomes to match. As a result, they … interactions are difficult to study in the lab. Metagenomics provides new views of these relationships.  … This shows that archaea may use CRISPR systems to protect against other, parasitic archaea. However, when  Ca . …
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How Maize Makes An Antibiotic Cocktail
… Maize produces a family of compounds that protects it against infections — using surprisingly few … in every corn variety and protect maize by fending off fungal and microbial infections. Scientists had assumed that … Program . And the work is part of a  larger CSP Functional Genomics proposal to understand terpene  synthesis and …
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Marchantia Pangenome Highlights Adaptive Nature of Plant Lineages
… In a recent  Nature Genetics paper , researchers focused on the full composition of genes, or pangenome, of the model … They hypothesized that certain gene families — including fungal genes horizontally transferred — contributed to the … plant lineages makes it ideal for comparative genomics studies, offering insight into genes critical for …
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Leo Baumgart
… San Diego. As the Sequencing Technology Implementation Lead, he directs a multidisciplinary team responsible for piloting and operationalizing new genomic … plant tissues. Dr. Baumgart focuses on expanding functional genomics capabilities through process automation and method …
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New Vision, New Mission, New Plan: The JGI’s Next Five Years
… strategic plan outlines how the JGI will advance the bioeconomy, leveraging partnerships to advance foundational … has released its newest 5-Year Strategic Plan: Innovating Genomics to Serve the Changing Planet (download a copy at … advance biotechnology and biomanufacturing.  As a leader in genomics for bioenergy and environmental solutions, the JGI …
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Mike Sneddon
… Dr. Sneddon is the Advanced Analysis Group Lead in the Data Science … leader in data, software, compute, and AI for large-scale genomics and lab informatics. Prior to joining JGI in late … S., Pelikan, C., Scannell, D., Serber, Z., Shock, J., Sneddon, M., and Yang, X. Metagenomic library and natural product …
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A Community Resource for Secondary Metabolite Researchers
… The Secondary Metabolism Collaboratory encourages user engagement. … come pre-annotated using multiple commonly used sequence analysis tools is a means of expediting BGC and biosynthesis … and viral BGC sequences. Expansion of the SMC to include fungal, plant, viral, and metagenome data is currently …
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Celebrating a Decade of Science through the JGI-UC Merced Genomics Internship Program
… 2023 marked a decade since the inception of the flagship internship program between the DOE Joint … summer of 2014 has grown to a total of 75 with the inclusion of the 2023 cohort. Each of them has brought invaluable … alumni, and other staff gathered at the Integrative Genomics Building, the JGI’s home at Berkeley Lab, as …
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A Complex Confection Decoded: Sugarcane Reference Genome
… work toward advancing sugarcane biotechnology. The Science Considered the world’s most harvested crop by tonnage, … rust disease resistance works in sugarcane could help protect other crops facing similar pathogens. Summary Many … the HudsonAlpha Institute for Biotechnology and the Arizona Genomics Institute. The work was partly enabled by the JGI’s …
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The More the Merrier: Making the Case for Plant Pan-genomes
… Brachypodium model system traces polyploid genome evolution. Flowering plants abide by the concept, “the more the … said John Vogel, head of the Plant Functional Genomics program at the JGI and a senior author on the … event (0.14 Mya) with a maternal  B. stacei parent. The analysis also revealed that these two  B. hybridum types …
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Tanja Woyke
… After studying the mechanism of action of antifungal natural products and their derivatives … deciphered function and host-symbiont interplay using metagenomics. Taking on a Research Scientist position in 2007, … The Deputy of User Programs provides direction, leadership and oversight for all of the JGI user …
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Gut Fungi: Unexpected Source of Novel Chemicals
… and help them digest their last leafy meal. In their evolutionary history, these fungi branched off early from aerobic … . Yet, combing through the genomes of four anaerobic fungal species has revealed, for the first time, that this … that these expressed genes translated into expected proteins. That work was done in collaboration with the …
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